Objective：To explore the effect of modified Kangfu Yutan tang combined with Xueshuantong injection on the nerve function and the activity of daily life of patients with sequelae of cerebral infarction.Methods：Divided 96 cases of patients with sequelae of cerebral infarction into two groups randomly，48 cases in each group.The two groups received routine treatment.The control group additionally received Xueshuantong injection for treatment，while the observation group additionally received Xueshuantong injection combined with modified Kangfu Yutan tang.The two groups were treated for one month continuously.Compared the scores of national institutes of health stroke scale(NIHSS)，Barthel index(BI)and levels of hemorheology indexes including plasma viscosity， fibrinogen(FIB)and hematocrit(HCT)before and after treatment， and calculated the total effective rate and the incidence of adverse reactions of the two groups.Results：The total effective rate was 91.67%in the observation group，higher than that of 70.83%in the control group，the difference being significant(P＜0.05).After one month of treatment，the NIHSS score in the observation was lower than that in the control group，while the BI score was higher than that in the control group，the difference being significant(P＜0.05).After one month of treatment，levels of plasma viscosity，FIB and HCT in the observation were lower than those in the control group，the difference being significant(P＜0.05).No significant difference was found in the comparison of the incidence of adverse reactions between the two groups(χ2=0.261，P＞0.05).Conclusion：The therapy of modified Kangfu Yutan tang combined with Xueshuantong injection has significant effect in treating patients with sequelae of cerebral infarction，which can effectively improve the hemorheology indexes，relieve the injury of neural function and improve the activity of daily life with high safety.