Objective:To observe the clinical effect of modified Jinshui Liujun jian combined with Shengmai powder for patients with chronic obstructive pulmonary disease(COPD)in stable phase.Methods:Randomly divided 60 cases of patients with COPD in stable phase who met the inclusion criteria into two groups,30 cases in each group.The control group was treated with western medicine,while the observation group was given modified Jinshui Liujun jian combined with Shengmai powder and western medicine.After six months of treatment,evaluated the scores of Chinese medicine symptoms,lung function, COPD Assessment Test(CAT)and the times of acute exacerbation in the two groups.Results:The scores of Chinese medicine symptoms after the third and the sixth month of treatment in the two groups were decreased when compared with those before treatment respectively,differences being significant(P<0.05).The scores of Chinese medicine symptoms after the third and the sixth month of treatment in the observation group were lower than those in the control group,differences being significant(P<0.05).After six months of treatment,there was no significant difference being found in the comparisons of the forced expiratory volume in one second(FEV1),the percentage of FEV1to forced vital capacity(FEV1/FVC),and the percent predicted(FEV1%)between the two groups when compared with those before treatment(P>0.05).The CAT scores after the third and the sixth month of treatment in the two groups were significantly decreased when compared with those before treatment,differences being significant(P<0.05).The two groups had fewer times of acute exacerbation during the first three-month treatment and during the third to the sixth month of treatment than during the three months before treatment,differences being significant(P< 0.05).The observation group had fewer timesof acute exacerbation during the third to the sixth month of treatment than the control group at the same period,the difference being significant(P<0.05).Conclusion:The therapy of modified Jinshui Liujun jian combined with Shengmai powder can improve the Chinese medicine symptoms and quality of life for patients with COPD in stable phase,and reduce the times of acute exacerbation.