益气活血解毒方联合针灸治疗幽门螺杆菌相关性胃病临床观察
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R573;R246.1

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Clinical Observation of Yiqi Huoxue Jiedu Prescription Combined with Acupuncture and Moxibustion for Gastric Disease Concerning Helicobacter Pylori
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    摘要:

    目的:观察益气活血解毒方配合针灸治疗幽门螺杆菌相关性胃病患者的临床治疗效果。方法:选择幽门螺杆菌相关性胃病患者274例,按随机数字表法分为观察组与对照组,每组137例。对照组给予基础药物治疗(兰索拉唑肠溶片+阿莫西林胶囊+克拉霉素胶囊),观察组采用针灸加用益气活血解毒方治疗。统计分析2组临床疗效,治疗前后主要症状体征(胃痛、胃胀、嗳气、少食)变化,治疗前后胃蛋白酶原I(PGI)、胃蛋白酶原II(PGII)、PGI/PGII指标的变化。结果:观察组与对照组的总有效率分别为98.54%、87.59%,2组比较,差异有统计学意义(P<0.05)。治疗前,2组胃痛、胃胀、嗳气、少食各项积分比较,差异无统计学意义(P>0.05)。治疗后,2组胃痛、胃胀、嗳气、少食各项积分较治疗前降低(P<0.05);观察组胃痛、胃胀、嗳气、少食各项积分显著低于对照组(P<0.05)。治疗前,2组PGI、PGII、PGI/PGII水平比较,差异无统计学意义(P>0.05)。治疗后,2组PGI、PGII、PGI/PGII水平较治疗前升高(P<0.05);观察组PGI、PGII、PGI/PGII水平高于对照组(P<0.05)。结论:益气活血解毒方联合针灸可以改善幽门螺杆菌相关胃病患者的临床症状体征,具有较高的临床治疗效果,同时有效提高胃蛋白酶原水平。

    Abstract:

    Objective:To observe the clinical effect of Yiqi Huoxue Jiedu prescription combined with acupuncture and moxibustion for patients with gastric disease concerning helicobacter pylori.Methods:Selected 274 cases of patients with gastric disease concerning helicobacter pylori,and divided them into the observation group and the control group randomly,137 cases in each group.The control group received basic medications(Lansoprazole enteric-coated tablets+Amoxicillin capsules+larithromycin Capsules)for treatment,while the observation group received acupuncture and moxibustion combined with Yiqi Huoxue Jiedu prescription.Statistically analyzed the clinical effect in both groups,changes of main symptoms and signs(stomachache,gastric distension,belching,poor appetite)before and after treatment,and changes of indexes of pepsinogen I(PGI)and pepsinogen II(PGII)and PGI/PGII before and after treatment.Results:The total effective rate was 98.54%in the observation group and 87.59%in the control group respectively,difference being significant(P<0.05).Before treatment,comparing each score of stomachache,gastric distension,belching and poor appetite in both groups,there was no significant difference being found(P>0.05).After treatment,each score of stomachache,gastric distension,belching and poor appetite in both groups was lower than that before treatment(P<0.05);each score of stomachache,gastric distension,belching and poor appetite in the observation group was significantly lower than that in the control group(P<0.05).Before treatment,comparing the levels of PGI,PGII and PGI/PGII in both groups,there was no significant difference being found(P>0.05).After treatment,the levels of PGI,PGII and PGI/PGII in both groups were higher than those before treatment(P<0.05);the levels of PGI,PGII and PGI/PGII in the observation group were significantly higher than those in the control group(P<0.05).Conclusion:Yiqi Huoxue Jiedu prescription combined with acupuncture and moxibustion can improve the clinical symptoms and signs of patients with gastric disease concerning helicobacter pylori.It has relatively high clinical effect and can enhance the level of pepsinogen effectively.

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鄢雪辉,郭婷婷,邓志燕,王杰.益气活血解毒方联合针灸治疗幽门螺杆菌相关性胃病临床观察[J].新中医,2018,50(12):97-100

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  • 在线发布日期: 2018-12-09
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