Objective：To explore the effect of Bailing capsules combined with metformin on metabolism indexes and sex hormone of polycystic ovary syndrome.Methods：Divided 107 cases of patients with polycystic ovary syndrome into the combination group and the control group by randomized double blind method，55 cases in the combination group and 52 cases in the control group.The two groups were treated with ethinylestradiol and cyproterone acetate tablets.The control group was additionally received metformin for treatment，while the combination group was additionally received Bailing capsules combined with metformin.After three months of continuous treatment，detected the changes in contents of lipid metabolism indexes and level of sex hormone in the two groups and compared the clinical effect.Results：After treatment，contents of triglyceride(TG)， total cholesterol(TC)， low density lipoprotein cholesterol(LDL-C)and high density lipoprotein cholesterol(HDL-C)in the two groups were significantly improved when compared with those before treatment，the difference being significant(P＜0.05)，and the contents of TG，TC，LDL-C and HDL-C in the combination group was significantly improved than that in the control group，the difference being significant(P＜0.05).After treatment，levels of testosterone(T)， estradiol(E2)， luteinizing hormone(LH)and follicle-stimulating hormone(FSH)in the two groups were significantly decreased when compared with those before treatment，the difference being significant(P＜0.05).Compared the decrease of level of E2between the two groups，there was no significance in the difference(P＞0.05).The decrease of levels of T，LH and FSH in the combination group was significantly greater than that in the control group(P＜0.05).Conclusion：The therapy of Bailing capsules combined with metformin for polycystic ovary syndrome can effectively regulate and improve the contents of lipid metabolism indexes and level of sex hormone as well as improve the clinical effect.