八珍益母胶囊联合西药治疗月经后期气血亏虚证临床观察
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R271.11+、P;R711.51

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Clinical Observation of Bazhen Yimu Capsules Combined with Western Medicine for Qi and Blood Deficiency Syndrome in the Late Menstrual Period
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    摘要:

    目的:观察八珍益母胶囊联合西药治疗月经后期气血亏虚证的疗效及对性激素水平的影响。方法:选取在本院就诊的110例月经后期气血亏虚证患者,按随机数字表法分为治疗组和对照组各55例。对照组口服戊酸雌二醇片与黄体酮胶囊,治疗组在对照组用药基础上予八珍益母胶囊治疗。2组均以3周为1疗程,连续治疗3疗程。比较2组治疗前后的气血亏虚证症状评分、血清性激素[促卵泡生成激素(FSH)、雌二醇(E2)、促黄体生成激素(LH)及泌乳素(PRL)]水平和临床疗效,记录2组的不良反应发生情况。结果:治疗后,治疗组总有效率90.91%,高于对照组的74.55%,差异有统计学意义(P<0.05)。2组气血亏虚证症状(头晕眼花、神疲乏力、少气懒言、面色苍白)评分均较治疗前下降(P<0.01);治疗组4项症状评分均低于对照组(P<0.01)。2组血清FSH、LH及PRL水平均较治疗前降低,E2水平均较治疗前升高,差异均有统计学意义(P<0.01);治疗组血清FSH、LH及PRL水平均低于对照组,E2水平高于对照组,差异均有统计学意义(P<0.01)。治疗组不良反应发生率为16.36%,对照组不良反应发生率为21.82%,2组比较,差异无统计学意义(P>0.05)。结论:在常规西药基础上加用八珍益母胶囊治疗月经后期气血亏虚证,可有效改善患者的症状,提高临床疗效,且安全性较好,调节患者的性激素水平可能与其疗效有关。

    Abstract:

    Objective:To observe the clinical effect of Bazhen Yimu capsules combined with western medicine for qi and blood deficiency syndrome in the late menstrual period and effect on sex hormone levels.Methods:Selected 110 cases of patients who received diagnoses with qi and blood deficiency syndrome in the late menstrual period and randomly divided them into the treatment group and the control group according to random number table,55 cases in each group.The control group was treated with progynova pills and progesterone capsules,while the treatment group was additionally treated with Bazhen Yimu capsules.The treatment for both groups lasted for 3 courses,3 weeks as a course.Compared the symptom scores of qi and blood deficiency syndrome,sex hormone levels in serum[follicle stimulating hormone(FSH),estradiol(E2),leuteinizing hormone(LH)and prolactin(PRL)]before and after treatment and the clinical effect in the two groups,and recorded the incidence of adverse reactions in the two groups.Results:After treatment,the total effective rate was 90.91%in the treatment group,being higher than that of 74.55%in the control group,difference being significant(P<0.05).The symptom scores of the qi and blood deficiency syndrome(dizziness and blurred vision,fatigue,lack of qi and no desire to speak,pale complexion)in two groups were decreased when compared with those before treatment(P<0.01);the previous four symptom scores in the treatment group were lower than those in the control group(P<0.01).The levels of FSH,LH and PRL in serum in the two groups were decreased when compared with those before treatment;and the E2level was increased when compared with those before treatment,differences being significant(P<0.01).The levels of FSH,LH and PRL in serum in the treatment group were lower than those in the control group;the level of E2was higher than that in the control group,differences being significant(P<0.01).The incidence of adverse reactions was 16.36%in the treatment group and 21.82%in the control group,difference being insignificant(P>0.05).Conclusion:Based on routine western medicine,the application of Bazhen Yimu capsules for qi and blood deficiency syndrome in the late menstrual period can effectively improve the symptoms of patients and promote the clinical effect.It is safer and its curative effect may be related to the regulation of the sex hormone levels in patients.

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王娅敏.八珍益母胶囊联合西药治疗月经后期气血亏虚证临床观察[J].新中医,2018,50(12):143-146

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  • 在线发布日期: 2018-12-09
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