Objective：To observe the clinical effect of local moving cupping therapy combined with blood-letting puncture and cupping therapy for psoriasis vulgaris.Methods：Divided 90 cases of patients with psoriasis vulgaris into three groups randomly，30 cases in each group.The routine treatment group received narrow-band ultraviolet B phototherapy and external application of halcinonide ointment for treatment；the moving cupping therapy group received local moving cupping therapy combined with blood-letting puncture and cupping therapy，and the combined treatment group additionally received local blood-letting puncture and cupping therapy based on the treatment of the routine treatment group.The treatment lasted for eight weeks.Observed the scores of psoriasis area and severity index(PASI)，evaluate the clinical effect and recorded the adverse reactions before and after treatment.Results：The total effective rate was 63.33%in the routine treatment group，56.67%in the moving cupping therapy group and 86.67%in the combined treatment group，and the total effective rate in the combined treatment group was better than that in the routine treatment group and that in the moving cupping therapy group，differences being significant(P＜0.05).After treatment，scores of PASI in the three groups were decreased when compared with those before treatment(P＜0.05).After treatment，compared the PASI score in the routine treatment group with that in the moving cupping therapy group，there was no significance in the difference(P＞0.05).PASI score in the combined treatment group was lower than that in the routine treatment group and that in the moving cupping therapy group，differences being significant(P＜0.05).No adverse reaction was found in the moving cupping therapy group.No significant difference was found in the comparison of the incidence of adverse reactions between the three groups(P＞0.05).Conclusion：The therapy of local moving cupping therapy combined with blood-letting puncture and cupping therapy for psoriasis vulgaris is safe and effective.The therapy combined with routine treatment can improve the therapeutic effect，which is worthy of application in clinical practice.