Obese type 2 diabetes mellitus(T2DM)is developing into an epidemic disease which is harmful to human health.The failure of the spleen to transport and transform，the failure of the liver to govern the free movement of qi，and the disorder of qi movement are mostly caused by constitution，emotion，diet and life style.Water，grain，fat and sweet food are transformed into phlegm-dampness and lipid accumulated in human body.The disharmony of the spleen and the liver plays an important role in the pathogenesis of this disease.Spleen deficiency and dampness stagnation is the constitutional basis of obese T2DM，and the disorder of qi movement is its important inducing condition.The clinical treatment of obese T2DM based on syndrome differentiation starts from spleen deficiency and the disorder of qi movement.The method of reinforcing the spleen and regulating the liver for obese type 2 diabetes mellitus is a kind of beneficial exploration.