稳心颗粒对高龄高血压合并左心功能不全患者血压、R-R间期的影响
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R544.1

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Effect of Wenxin Granules on Blood Pressure and R-R Interval in Senile Patients with Hypertension Complicated with Left Cardiac Insufficiency
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    摘要:

    目的:观察稳心颗粒对高龄高血压(HBP)合并左心功能不全患者血压、R-R间期相关指标的影响。方法:将86例高龄HBP伴有左心功能不全患者按照随机数字表法分为2组各43例,对照组口服卡托普利片,联合组在对照组治疗基础上联合应用稳心颗粒,均治疗1个月。比较2组患者治疗前和治疗后1个月血压(收缩压、舒张压)和R-R间期相关指标,并记录2组患者不良反应的发生情况。结果:2组治疗前血压水平的比较,差异无统计学意义(P>0.05);2组治疗后血压较治疗前均降低,且联合组降低幅度较对照组更为显著(P<0.05)。2组治疗前R-R间期相关指标比较,差异无统计学意义(P>0.05);2组治疗后,R-R间期相关指标较治疗前上升,且联合组上升幅度较对照组更为显著(P<0.05)。对照组不良反应总发生率为11.63%,联合组不良反应总发生率为6.98%,2组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:在口服卡托普利片作为常规治疗的同时,应用稳心颗粒可有效改善高龄HBP伴有左心功能不全患者的血压水平,改善患者心功能,具有良好的安全性。

    Abstract:

    To observe the effect of Wenxin granules on blood pressure and R-R interval related indexes in elderly patients with high blood pressure(HBP)complicated with left cardiac insufficiency.Methods:A total of 86 cases of HBP patients with left cardiac insufficiency were divided into two groups according to random number table method,43 cases in each group.The control group was treated with oral administration of captopril tablets,and the combination group was additionally treated with Wenxin granules based on the treatment of the control group.Both groups were treated for one month.Blood pressure(systolic pressure and diastolic pressure)and R-R interval related indexes were compared between the two groups of patients before treatment and one month after treatment,and the occurrence of adverse reactions in the two groups was recorded.Results:There was no statistically significant difference in the comparison of blood pressure between the two groups before treatment(P>0.05).The levels of blood pressure in both groups were decreased after treatment when compared with those before treatment,and the decrease in the combination group was more significant than that in the control group(P<0.05).There was no statistically significant difference in the comparison of the R-R interval related indexes between the two groups(P > 0.05).After treatment,the indexes of R-R interval were increased when compared with those before treatment in the two groups,and the increase in the combination group was more significant than that in the control group(P<0.05).The total incidence of adverse reactions was 11.63%in the control group and 6.98%in the combination group,there being no statistically significant difference(P > 0.05).Conclusion:Based on the captopril as a routine treatment,the additional application of Wenxin granules can effectively improve the level of blood pressure and improve the cardiac function of elderly patients with HBP complicated with left cardiac insufficiency,which is safe.

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徐晶晶.稳心颗粒对高龄高血压合并左心功能不全患者血压、R-R间期的影响[J].新中医,2019,51(10):84-86

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  • 在线发布日期: 2019-10-11
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