Observation of Bushen Huayu Prescription Combined with Transcervical Resection of AdhesionforHypomenorrheaofIntrauterineAdhesionsTypeandItsEffecton Endometrial Thickness
To observe the curative effect of Bushen Huayu prescription combined with transcervical resection of adhesion(TCRA)for patients with hypomenorrhea(amenorrhea)of intrauterine adhesions(IUA)type and its effect on endometrial thickness.Methods:A total of 97 cases of patients with hypomenorrhea of IUA type were numbered according to the visiting time and were randomly divided into the treatment group and the control group,49 and 48 cases in each group respectively.Patients in the two groups were treated with TCRA three to seven days after menstruation,and there was no time restriction for the patients with amenorrhea.On the 3rdday after surgery,the treatment group was treated with Bushen Huayu prescription,and the control group was treated with Bujiale.Both groups were treated for three menstrual cycles.Before and after treatment,the duration,amount,colors and quality of menstruation,the endometrial thickness on the 14th and 25thday in menstrual periods,the degree of IUA,and the changes of tumor necrosis factor-α (TNF-α)and interleukin-6(IL-6)at different time were observed and recorded.Results:After treatment,the Chinese medicine syndrome scores in the two groups were decreased when compared with those before treatment,the difference being significant(P < 0.05);the comparison of the scores in the two groups showed significance in the difference(P < 0.05).After treatment,the endometrial thicknesses on the 14thand 25thday in the two groups were increased when compared with those before treatment,and the increase in the treatment group was more obvious,the difference being significant(P < 0.05).After treatment,the scores of IUA in the two groups were decreased,and the decrease in the treatment group was more obvious,the difference being significant(P<0.05).One hour after surgery,the contents of TNF-α and IL-6 in the two groups were increased when compared with those before surgery;three and seven days after surgery,the above two contents were decreased when compared with those before treatment,and the decrease in the treatment group was more obvious,the difference being significant(P < 0.05).After treatment,there was no significant difference being found in the comparison of the pregnancy in the two groups(P>0.05).There was no obvious adverse reaction in the two groups during the study.Conclusion:The therapy of Bushen Huayu prescription combined with TCRA can effectively repair the endometrial thickness,increase menstrual amount, improve the amount, color and quality of menstrual blood, and reduce postoperative inflammatory reaction of TCRA.