To observe the effect of moxibustion combined with dietary guidance of Chinese medicine on blood glucose，blood lipid and quality of life in patients with diabetes mellitus(DM)of qi deficiency and phlegm turbidity type.Methods：A total of 140 cases DM patients of qi deficiency and phlegm turbidity type were randomly divided into the control group and the treatment group，70 cases in each group.The control group was given symptomatic treatments such as lowering blood glucose，blood lipid and blood pressure，and the treatment group was additionally given moxibustion and dietary guidance of Chinese medicine based on the treatment of the control group.Both groups were continually intervened for 20 weeks.The changes of the scores of blood glucose，blood lipid，qi deficiency and phlegm turbidity syndrome and Diabetes Specificity Quality of Life Scale(DSQL)before and after treatment were observed.Results：After treatment，the levels of fasting blood glucose(FBG)，postprandial 2-hour blood glucose(P2hBG)and hemoglobin A1c(HbA1c)in the two groups were decreased when compared with those before treatment(P ＜ 0.01)，and the above levels in the treatment group were lower than those in the control group(P ＜ 0.01).After treatment，the levels of total cholesterol(TC)，triglyceride(TG)and low-density lipoprotein cholesterol(LDL-C)in the two groups were decreased when compared with those before treatment(P＜0.01)，while the levels of high-density lipoprotein cholesterol(HDL-C)were increased when compared with those before treatment(P ＜ 0.01)；the levels of TC，TG and LDL-C in the treatment group were lower than those in the control group(P ＜ 0.01)，while the level of HDL-C was higher than that in the control group(P ＜ 0.01).After treatment，the scores of qi deficiency and phlegm turbidity syndrome and DSQL in the two groups were decreased when compared with those before treatment(P＜0.01)，and the above scores in the treatment group were lower than those in the control group(P ＜ 0.01).Conclusion：The intervention of moxibustion combined with dietary guidance of Chinese medicine in treating DM patients of qi deficiency and phlegm turbidity type can improve the control effect of blood glucose，regulate lipid metabolism，alleviate clinical symptoms and improve quality of life.