To observe the effect of Chinese medicine emotional nursing on patients with hyperthyroidism complicated with anxiety and depression.Methods：A total of 96 cases of patients with hyperthyroidism complicated with anxiety and depression were divided into the control group and the observation group according to random number table method，46 cases in each group.Both groups were treated with Thiamazole tablets and Shugan Jieyu capsules； the control group was additionally given routine nursing，and the observation group was additionally treated with Chinese medicine emotional nursing based on the treatment of the control group.Eight weeks after treatment，the therapeutic effect was evaluated； the scores of Hamilton Anxiety Scale(HAMA)，Hamilton Anxiety Scale-17(HAMA-17)，Pittsburgh Sleep Quality Index(PSQI)and subjective emotional symptoms were compared before and after treatment in the two groups.Results：After treatment， scores of HAMA， HAMA-17 and PSQI in both groups were decreased when compared with those before treatment(P＜0.01)，and the ones in the observation group were lower than those in the control group(P＜0.01).After treatment，the scores of susceptibility to fright and fear，preference to sigh，haziness of spirit-affect，moodiness，and vexation and irritability in the two groups were all decreased when compared with those before treatment(P ＜ 0.01)，and the scores of the above subjective emotional symptoms in the observation group were lower than those in the control group(P＜0.01).Conclusion：Chinese medicine emotional nursing can effectively reduce depression and anxiety in patients with hyperthyroidism，improve their quality of sleep，and reduce adverse subjective emotional symptoms.