Objective：To observe the curative effect of Shentong Zhuyu tang for patients with hand fracture and the effect on the regression time of swelling of the hands and the recovery of hand function.Methods：Selected 76 cases of patients with hand fracture enrolled in Pingding shan First People's Hospital from July in 2016 to June in 2018 and divided them into two groups according to different treatment methods.Both groups were treated with mini-plate and adopted routine functional exercise after operation and the observation group was additionally given the oral administration of Shentong Zhuyu tang.Analyzed the clinical effect after treatment in the two groups.Results：The whole blood viscosity(in high shear rate and low shear rate)，plasma viscosity and hematocrit in the two groups were all decreased when compared with those before treatment(P ＜ 0.05)；the levels of Serum insulin-like growth factor-I(IGF-I)；Bone morphogenetic protein-2(BMP-2)were increased when compared with those before treatment(P＜0.05).Compared with the control group after treatment，the detumescence time of swelling of the hands，hospitalization time and healing time in the observation group were shorter(P＜0.05)，the whole blood viscosity(in high shear rate and low shear rate)and plasma viscosity were decreased(P ＜ 0.05)，the levels of IGF-I and BMP-2 were increased(P＜0.05)and there was no significant difference being found in the comparison of the hematocrit(P＞0.05).The excellent and good rate was 94.73% in the observation group and 78.95% in the control group，difference being significant(P＜0.05).Conclusion：The application of Shentong Zhuyu tang for patients with hand fracture can improve the indexes of hemorheology in patients，enhance the expression levels of IGF-I and BMP-2 and promote the reduction of swelling，the healing of the bone and the recovery of hand function.