加减玉屏风散联合孟鲁司特钠治疗成人支气管哮喘缓解期临床研究
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R562.2+5

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Clinical Study on Modified Yupingfeng Powder Combined with Montelukast Sodium for Bronchial Asthma at Remission Stage in Adult
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    摘要:

    目的:观察加减玉屏风散联合孟鲁司特钠治疗成人支气管哮喘缓解期的临床疗效。方法:将成人支气管哮喘缓解期患者80 例随机分为对照组和观察组,各40 例,对照组给予孟鲁司特钠治疗,观察组给予加减玉屏风散联合孟鲁司特钠治疗,所有患者均治疗3 个月;观察比较2 组血清免疫细胞水平、病情严重程度与总体临床疗效。结果:治疗后,2 组患者CD4+、CD4+/CD8+值均比治疗前降低(P<0.05),CD8+值均比治疗前升高(P<0.05);且观察组上述各项指标改善较对照组更显著(P<0.05)。治疗后,病情程度重度率观察组为2.5%,对照组为22.5%,2 组比较,差异有统计学意义(P<0.05)。总有效率观察组为97.5%,对照组为77.5%,2 组比较,差异有统计学意义(P<0.05)。结论:加减玉屏风散联用孟鲁司特钠治疗成人支气管哮喘缓解期效果显著。

    Abstract:

    Abstract:Objective:To observe the clinical effect of modified Yupinfeng Powder combined with montelukast sodium for bronchial asthma at the remission stage in adult. Methods:A total of 80 cases of adult patients with bronchial asthma at the remission stage were randomly divided into the control group and the observation group,40 cases in each group. The control group was given montelukast sodium,and the observation group was additionally treated with modified Yupingfeng powder based on the treatment of the control group. Both groups were treated for three months. The level of immune cells in serum, the disease severity and total clinical effect were observed and compared between the two groups. Results: After treatment,the values of CD4+ and CD4+/CD8+ in the two groups were decreased when compared with those before treatment (P<0.05),and the values of CD8+ were increased when compared with those before treatment(P<0.05);the improvement of the three indexes above in the observation group was more significant than that in the control group(P<0.05). After treatment,the rate of disease severity was 2.5% in the observation group and 22.5% in the control group,the difference being significant(P<0.05). The total effective rate was 97.5% in the observation group and 77.5% in the control group,the difference being significant(P<0.05). Conclusion: The therapy of modified Yupinfeng powder combined with montelukast sodium has significant application effect in treating adult patients with bronchial asthma at the remission stage.

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李敏杰,钱跃磊,魏嘉,朱树艳.加减玉屏风散联合孟鲁司特钠治疗成人支气管哮喘缓解期临床研究[J].新中医,2020,52(18):76-78

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  • 在线发布日期: 2020-09-20
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