Abstract： Objective： To observe the clinical effect of Gugutou Huaisiyu capsules and bisphosphonates for avascular necrosis of femoral head(ANFH) after surgery for displaced fractures of femoral neck. Methods：A total of 55 cases of ANFH patients after surgery for displaced fractures of femoral neck in our hospital were divided into the observation group and the control group according to the random number table method group， 30 and 25 cases in each group respectively. After surgery， both groups were given routine symptomatic treatment； the observation group was additionally treated with Gugutou Huaisiyu capsules，and the control group was additionally treated with bisphosphonate(Alendronate sodium). After six-month treatment，the clinical effect，the pain，the hip joint function and the recovery of functional independence were compared between the two groups. The blood routine as well as the function of the liver and the kidney were detected to evaluate the safety of medicine. Results：The total effective rate was 90.48% in the observation group，significantly higher than that of 67.65% in the control group， the difference being significant(P＜0.05). After treatment， the scores of Visual Analogue Scale(VAS) in the two groups were decreased when compared with those before treatment，and the score in the observation group was lower than that in the control group，the difference being significant(P＜0.05). After treatment，the score of the hip joint function(Harris) and Functional Independence Measure(FIM) in the two groups were increased when compared with those before treatment，and the two scores in the observation group were higher than those in the control group(P＜0.05). There was no adverse medicine reaction in the two groups during treatment. Conclusion：In the treatment of ANFH after surgery for displaced fractures of femoral neck， compared with simple bisphosphonates， Gugutou Huaisiyu capsules is conductive to enhancing clinical effect，effectively relieving pain，improving the hip joint function，and recovering functional independence with high safety.