Objective： To discuss the clinical effect of heat-reinforcing needling combined with Heiguteng Zhuifeng Huoluo capsules for rheumatoid arthritis of wind-cold and fixed impediment type.Methods：A total of 140 cases of patients with rheumatoid arthritis of wind-cold and fixed impediment type were randomly divided into four groups.The control group(37 cases)was treated with routine western medicine.Based on the treatment of the control group，the observation group A(33 cases)was additionally treated with heat-reinforcing needling，the observation group B(36 cases)was additionally treated with Heiguteng Zhuifeng Huoluo capsules，and the observation group C(34 cases)was additionally treated with heatreinforcing needling combined with Heiguteng Zhuifeng Huoluo capsules.All groups were treated for three months.In order to analyze the clinical effect of different treatment before and after treatment in the four groups，the following indexes were measured and compared，including the total effective rates，the levels of erythrocyte sedimentation rate(ESR)，C-reactive protein(CRP)and rheumatoid factor(RF)in serum， the content of interleukin-17A(IL-17A)， interleukin-18(IL-18)and interleukin-27(IL-27)in synovial fluid， the changes of signs of tender joint count， joint swollen indexes， rest pain and duration of morning stiffness and the adverse responses.Results：The clinical effect in the observation group C was significantly better than that in the other three groups(P ＜ 0.05)；the clinical effect in the observation group A and the observation group B was significantly better than that in the control group(P ＜ 0.05).After treatment，the tender joint counts，swollen joint counts，joint swollen indexes，scores of rest pain and duration of morning stiffness in the four groups were decreased when compared with those before treatment(P ＜ 0.05)，and the average hand grip strength was increased when compared with that before treatment(P ＜ 0.05).In the observation group C，the tender joint count，swollen joint count，joint swollen indexes，scores of rest pain and duration of morning stiffness were lower than those in the other three groups(P ＜0.05)，and the average hand grip strength was higher than those in the other three groups(P ＜ 0.05).The tender joint counts，swollen joint counts，joint swollen indexes，scores of rest pain and duration of morning stiffness in the observation group A and B were lower than those in the control group(P＜ 0.05)；the duration of morning stiffness in the observation group B was significantly longer than that in the observation group A(P＜ 0.05).After treatment，the levels of CRP，RF and ERS in serum in the four groups were decreased when compared with those before treatment(P＜0.05).The levels of CRP，RF and ERS in serum in the observation group C were lower than those in the other three groups(P ＜ 0.05)；the levels of RF and ERS in serum in the observation group A and B were lower than those in the control group(P＜ 0.05)；the level of ERS in serum in the observation group B was lower than that in the observation group A(P＜ 0.05).After treatment，the content of IL-17A，IL-18and IL-27 in synovial fluid in the four groups were significantly decreased when compared with those before treatment(P＜0.05).The content of IL-17A，IL-18 and IL-27 in the observation group A was lower than that in the control group(P ＜ 0.05)；the content of IL-17A and IL-18 in the observation group B was lower than that in the control group and the observation group A，and the content of IL-27 was lower than that in the control group(P＜0.05).Conclusion：The therapy of heatreinforcing needling combined with Heiguteng Zhuifeng Huoluo capsules has good curative effect in treating rheumatoid arthritis of wind-cold and fixed impediment type，and can be further promoted in clinic.