Objective：To observe the effect of Chinese medicine emotional nursing combined with point-application on the emotion and quality of life in postoperative patients with operation for brain injury.Methods：Divided 108 cases of patients into the control group with 52 cases and the observation group with 56 cases randomly；both groups adopted the comprehensive western medicine nursing measures instructed by psychological nursing，complication prevention，nutritional support and rehabilitation nursing；the observation group was additionally given the intervention of Chinese medicine emotional nursing combined with point-application and the course of treatment in both groups was 4 weeks；observed and compared the scores of self-rating anxiety scale(SAS)，self-rating depression scale(SDS)， self-esteem scale(SES)，ability of daily life(ADL)and health SF-36 scale[including the general health(GH)，vitality(VT)，social function(SF)，emotional role(RE)， mental health(MH)， physiological function(PF)， physiological role(RP)， body pain(BP)]in the two groups before and after treatment；and evaluated the nursing satisfaction of patients.Results：After treatment，the scores of SAS and SDS in the two groups were obviously decreased when compared with those before treatment(P＜ 0.05)；and the scores of SAS and SDS in the observation group were lower than those in the control group(P＜ 0.05).After treatment，the SES scores in the two groups were obviously increased when compared with those before treatment(P ＜ 0.05)，while the ADL scores were obviously decreased(P ＜ 0.05)；and the improvement of the scores of SES and ADL in the observation group was more evident than that in the control group(P ＜ 0.05).After treatment，the scores of GH，VT，SF，RE，MH，PF，RP and BP in the two groups were obviously increased when compared with those before treatment(P ＜ 0.05)；and all the scores mentioned above in the observation group were higher than those in the control group(P＜0.05).Rank sum test showed that the nursing satisfaction of patients in the observation group was better than that in the control group，difference being significant(P＜0.05).Conclusion：The intervention of Chinese medicine emotional nursing combined with point-application on postoperative patients with operation for brain injury has evident curative effect，which can reduce the degree of anxiety and depression of patients，enhance the degree of self-esteem and living ability of patients and evidently improve the quality of life of patients.It is worthy of clinical promotion and application.