Abstract：Objective：To observe the curative effect of modified Shentong Zhuyu tang combined with celecoxib capsules for axial symptoms after surgery of multilevel cervical myelopathy. Methods：A total of 60 cases of patients with multilevel cervical myelopathy who had axial symptoms after receiving unilaterally- open expansive laminoplasty through posterior approach，were randomly divided into the control group and the treatment group，30 cases in each group. The control group was treated with celecoxib capsules，and the treatment group was additionally given modified Shentong Zhuyu tang based on the treatment of the control group. The administration lasted for four weeks in both groups. Before treatment and after the four-week treatment，Neck Disabilitr Index(NDI) was used to evaluate the cervical function of the two groups，the scores of Visual Analogue Scale(VAS) and Range of motion(ROM) of cervical joint were recorded. The curative effect and the incidence of adverse reactions were compared between the two groups. Results：After four-week treatment，the scores of VAS and NDI were decreased in the two groups(P＜0.05)，and the cervical ROM were increased(P＜0.05)；the scores of VAS and NDI in the treatment group were lower than those in the control group(P＜0.05)，and the cervical ROM was higher(P＜0.05). The total effective rate was 96.7% in the treatment group， and 83.3% in the control group， the difference being significant between the two groups(P＜0.05). During treatment，there was no obvious adverse reactions in the two groups. Conclusion： For patients with axial symptoms after surgery of multilevel cervical myelopathy，the therapy of modified Shentong Zhuyu tang combined with celecoxib capsules has significant clinical effect，which can effectively relieve cervical pain，improve the function of cervical spine，and alleviate the dysfunction of cervical spine.