Abstract：Objective：To observe the clinical effect of Waiyong Kuiyang San combined with loop electrosurgical excision procedure(LEEP)for cervical intraepithelial neoplasia(CIN). Methods： A total of 130 cases of CIN patients were randomly divided into the control group and the treatment group，65 cases in each group. The control group was treated with cervical conization by LEEP knife，and the treatment group was treated with LEEP combined with Waiyong Kuiyang San. The scores of symptoms and signs including erosive area， vaginal cleanliness and leucorrhea before and after surgery， the time of vaginal bleeding， vaginal fluid and wound healing after surgery， postoperative complications and total clinical effect in the two groups were observed and compared. Results：The total effective rate was 92.31% in the treatment group and 80.00% in the control group， the difference being significant(P＜0.05). After treatment， the scores of erosive area， vaginal cleanliness and leucorrhea in the two groups were all decreased when compared with those before treatment(P＜0.05)，and the above scores in the treatment group were significantly lower than those inthe control group(P＜0.05). After treatment， the amount of postoperative vaginal bleeding and vaginal fluid in the treatment group was significantly lower than that in the control group(P<0.05)， and the wound healing time was shorter than that in the control group(P＜0.05). The incidence of postoperative complications was 3.08% in the treatment group and 15.38% in the control group， the difference being significant(P＜0.05). Conclusion： Compared with the simple treatment of cervical conization by LEEP knife， the additional application ofWaiyong Kuiyang San has definite curative effect，which can better improve the clinical symptoms and signs of patients，shorten the time of postoperative bleeding and wound healing，and reduce postoperative complications，and it is worthy of clinical promotion and application.