Abstract：Objective：To observe the clinical effect of Runchang pills and Huangqi tang combined with routine therapy for senile severe functional constipation(FC). Methods： A total of 90 cases of patients of qi- yin(blood) deficiency type were randomly divided into the control group and the observation group，45 cases in each group. In both groups，their life styles were regulated； they were given oral administration of mosapride citrate tablets， bifidobacterium triple viable capsules dissolving at intestines， and lactulose oral solution. The observation group was additionally given oral administration of modified Runchang pills and Huangqi tang. Both groups were treated for six weeks. Before and after treatment，scores of the main symptoms of constipation，score of Patient Assessment of Constipation Quality of Life Scale(PAC-QOL)，and score of qi- yin(blood) deficiency syndrome were evaluated. The weekly frequency of complete spontaneous bowel movements (CSBM) at the 1st week before treatment and one week after treatment was recorded， and anorectal manometry was conducted. Anal resting pressure(ARP)， maximum squeeze pressure(MSP)， MSP duration and defecation pressure were recorded. The curative effect was compared between the two groups. Results： After treatment， the scores of the main symptoms of constipation in the two groups， such as fecal character， difficult defecation， defecation time， defecation frequency，abdominal distension and straining sensation，incomplete defecation and distending sensation，were decreased when compared with those before treatment(P＜0.01)；the above six scores in the observation group were lower than those in the control group(P＜0.01). The scores of qi- yin(blood) deficiency syndrome in the two groups were decreased when compared with those before treatment(P＜0.01)，and the weekly frequency of CSBM was increased(P＜0.01). The score of qi-yin(blood) deficiency syndrome in the observation group was lower than that in the control group(P＜0.01)，and the weekly frequency of CSBM was higher(P＜0.01). In the two groups， ARP， MSP and defecation pressure were increased when compared with those before treatment(P＜0.01)， and the largest MSP duration was prolonged when compared with that before treatment(P＜0.01). In the observation group， ARP， MSP and defecation pressure were higher than those in the control group(P＜0.01)，and the largest MSP duration was longer than that in the control group(P＜0.01). In the two groups， scores of four dimensions，namely physiology，psychology，worry and satisfaction in PAC-QOL，and the total score were decreased when compared with those before treatment(P＜0.01)， and score of each dimension and the total score in the observation group were lower than those in the control group(P＜0.01). The curative effect of Chinese medicine syndrome in the observation group was better than that in the control group(P＜0.05). Conclusion： Based on routine treatment， the additional oral administration of modified Runchang pills and Huangqi tang in treating patients with senile severe FC of qi-yin (blood) deficiency type，can further relieve constipation symptoms，increase the time of CSBM，promote recovery of normal intestinal motility， and improve patients' quality of life， with significant improvement in the curative effect of Chinese medicine syndrome.