结合雌激素乳膏联合加味知柏地黄汤熏洗治疗反复发作老年性阴道炎临床研究
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R711.31

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Clinical Study on Conjugated Estrogens Cream Combined with Fumigation and Wash⁃ing with Modified Zhibai Dihuang Tang for Recurrent Senile Vaginitis
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    摘要:

    目的:观察结合雌激素乳膏联合加味知柏地黄汤治疗反复发作老年性阴道炎的临床疗效。方法:将118例反复发作老年性阴道炎患者随机分为对照组和观察组各59例。对照组予结合雌激素乳膏联合复方甲硝唑栓治疗,观察组予结合雌激素乳膏联合加味知柏地黄汤熏洗治疗。治疗2 周后,比较2 组临床疗效、阴道清洁度、阴道健康评分、阴道炎症状评分,随访6 个月,记录复发情况。结果:治疗后,观察组临床疗效优于对照组(P<0.05)。与治疗前比较,治疗后2 组阴道清洁度显著好转(P<0.01),且观察组阴道清洁度情况优于对照组(P<0.05);治疗后2组阴道健康情况显著改善(P<0.01),且观察组阴道健康情况优于对照组(P<0.05);治疗后2组阴道健康评分明显升高(P<0.01),阴道炎症状评分显著下降(P<0.01),且观察组阴道健康评分高于对照组(P<0.01),阴道炎症状评分低于对照组(P<0.01)。随访期间,观察组复发率为8.77%,低于对照组的26.92%(P<0.05)。结论:结合雌激素乳膏联合加味知柏地黄汤治疗反复发作老年性阴道炎可以减轻阴道炎症状,提高阴道健康状况,改善阴道内环境,降低复发率。

    Abstract:

    Abstract: Objective: To observe the clinical effect of conjugated estrogens cream combined with modified Zhibai Dihuang tang for recurrent senile vaginitis. Methods: A total of 118 cases of patients with recurrent senile vaginitis were randomly divided into the control group and the observation group, 59 cases in each group. The control group was given conjugated estrogens cream combined with compound metronidazole suppositories,and the observation group was treated with conjugated estrogens cream combined with fumigation and washing with modified Zhibai Dihuang tang. After two-week treatment,the clinical effect,the degree of vaginal cleanliness,the condition and scores of vaginal health,and the scores of vaginitis symptoms were compared between the two groups. The recurrence was recorded during six-month following up.Results:After treatment,the clinical effect in the observation group was better than that in the control group(P<0.05). The degree of vaginal cleanliness in the two groups was significantly improved when compared with that before treatment(P<0.01), and the degree in the observation group was better than that in the control group(P<0.05). After treatment, the condition of vaginal health in the two groups were significantly improved(P<0.01),and the condition in the observation group was better than that in the control group(P<0.05). After treatment, the scores of vaginal health in the two groups were significantly increased(P<0.01),and the scores of vaginitis symptoms were significantly decreased(P<0.01);the score of vaginal health in the observation group was higher than that in the control group(P<0.01), and the score of vaginitis symptoms was lower than that in the control group(P<0.01). During the following up,the recurrence rate was 8.77% in the observation group, lower than that of 26.92% in the control group(P<0.05). Conclusion: The application of conjugated estrogens cream combined with modified Zhibai Dihuang tang has good clinical effect in treating recurrent senile vaginitis. In the short term, it can alleviate vaginitis symptoms, and improve the condition of vaginal health and vagina internal environment. In the long term,the recurrence rate can be reduced.

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高微微.结合雌激素乳膏联合加味知柏地黄汤熏洗治疗反复发作老年性阴道炎临床研究[J].新中医,2020,52(12):28-31

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  • 在线发布日期: 2020-06-15
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