Clinical Study on Modified Maxing Shigan Tang Combined with Aerosol Inhalation of Terbutaline and Budesonide for Acute Attack of Bronchial Asthma in Children
Abstract:Objective:To observe the clinical effect of modified Maxing Shigan tang combined with aerosol inhalation of terbutaline and budesonide for acute attack of bronchial asthma in children. Methods: A total of 94 cases of children with acute attack of bronchial asthma were divided into the control group and the observation group according to the random number table method, 47 cases in each group. The control group was treated with aerosol inhalation of terbutaline and budesonide based on routine treatment, and the observation group was additionally treated with modified Maxing Shigan tang based on the treatment of the control group. The clinical effect and indexes of the lung function before and after treatment were compared between the two groups. The incidence of adverse reactions during treatment was observed. Results:After treatment,the total clinical effective rate was 97.78% in the observation group,higher than that of 85.11% in the control group, the difference being significant(P<0.05). Before treatment, there was no significant difference being found in the comparison of the forced expiratory volume in one second(FEV1) and peak expiratory flow(PEF) between the two groups(P>0.05). After treatment,the levels of FEV1 and PEF in the two groups were increased when compared with those before treatment(P<0.05),and the above two levels in the observation group were higher than those in the control group(P< 0.05). Before treatment,when compared the symptom scores of asthma,wheezing in the larynx,cough and expectoration between the two groups, there was no significance being found in the difference(P>0.05); after treatment, the above symptom scores in the two groups were all decreased when compared with those before treatment(P<0.05),and the scores in the observation group were all lower than those in the control group(P<0.05). Conclusion:The therapy of modified Maxing Shigan tang combined with aerosol inhalation of terbutaline and budesonide is conductive to improving the lung function and clinical symptoms in children with acute attack of bronchial asthma,with significant curative effect,safety and reliability.