克感利咽口服液辅助治疗儿童急性化脓性扁桃体炎临床研究
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R766.18

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Clinical Study on Kegan Liyan Oral Lipid in Adjuvant Therapy of Acute Suppurative Tonsillitis in Children
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    摘要:

    目的:观察克感利咽口服液辅助治疗儿童急性化脓性扁桃体炎(风热搏结证) 的临床疗效。方法:将150 例患儿随机分为观察组75 例和对照组75 例。对照组患儿若症状轻者给予口服头孢克洛干混悬剂口服,症状重者给予注射用阿奇霉素静脉滴注,体温≥38.5 ℃者给予布洛芬混悬液口服;观察组在对照组的基础上给予克感利咽口服液口服。观察比较2 组咽痛视觉模拟评分法(VAS) 评分、风热搏结证评分、体温降至正常时间、咽部充血消退时间及脓性分泌物消失时间,检测2 组治疗前后白细胞(WBC) 计数、中性粒细胞(N)、C-反应蛋白(CRP) 水平变化。结果:总有效率观察组为100%,对照组为96.00%;2 组临床疗效经秩和检验,差异有统计学意义(P<0.05),观察组疗效优于对照组。观察组退热时间、脓性分泌物消失时间、咽部充血消退时间均明显短于对照组,差异有统计学意义(P<0.05)。治疗后3 d、5 d、7 d、10 d,2 组患儿咽痛VAS 评分均较治疗前明显降低(P<0.05);且观察组在各个时间点的咽痛VAS 评分均低于对照组(P<0.05)。治疗后,2 组患儿WBC、N、CRP 值均较治疗前明显降低(P<0.05);且观察组上述各项指标均明显低于对照组(P<0.05)。结论:克感利咽口服辅助治疗儿童急性化脓性扁桃体炎风热搏结证患者,可显著减轻咽痛,缩短病程,减轻炎症反应,临床疗效显著。

    Abstract:

    Abstract: Objective: To observe the clinical effect of Kegan Liyan oral lipid in adjuvant therapy of acute suppurative tonsillitis with the syndrome of wind-heat and pathogenic toxin invading the lung in children. Methods:A total of 150 cases of children were randomly divided into the observation group and the control group, 75 cases in each group. In the control group, the oral administration of cefaclor for suspension was for children with mild symptoms, the intravenous drip of azithromycin for injection for those with severe symptoms, and the oral administration of ibuprofen suspension for those whose body temperature was at 38.5 ℃ or above. The observation group was additionally given oral administration of Kegan Liyan oral lipid based on the treatment of the control group. The scores of Visual Analogue Scale(VAS) and the syndrome of wind- heat and pathogenic toxin invading the lung, the time for temperature back to normal, the regression time of pharyngeal hyperemia and the disappearance time of purulent secretion were observed and compared between the two groups. The changes in the levels of white blood cell(WBC) count,neutrophil(N) and C-reactive protein(CRP) before and after treatment were detected in the two groups. Results:The total effective rate was 100% in the observation group and 96.00% in the control group;the difference being significant(P<0.05),and the curative effect in the observation group was better than that in the control group. The fever subsidence time,the disappearance time of purulent secretion and the regression time of pharyngeal hyperemia in the observation group were significantly shorter than those in the control group, the difference being significant(P<0.05). On the 3rd,5th,7th and 10th days after treatment,the VAS scores of sore throat in the two groups were significantly decreased when compared with those before treatment(P<0.05);the scores at different time points in the observation group were lower than those in the control group(P<0.05). After treatment,the values of WBC,N and CRP in the two groups were significantly decreased when compared with those before treatment(P<0.05);the above three indexes in the observation group were significantly lower than those in the control group(P<0.05). Conclusion: In adjuvant therapy for children with acute suppurative tonsillitis with the syndrome of wind-heat and pathogenic toxin invading the lung, Kegan Liyan oral lipid can significantly alleviate sore throat, shorten the course of the disease and relieve inflammatory responses with significant clinical effect.

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梁锐,成莎.克感利咽口服液辅助治疗儿童急性化脓性扁桃体炎临床研究[J].新中医,2020,52(15):86-89

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  • 在线发布日期: 2020-08-08
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