Abstract：Objective：To observe the clinical effect of Yangjing Jingjin Paici method combined with rehabilitation training for shoulder-hand syndrome at stageⅠafter stroke. Methods：A total of 120 cases of patients with shoulder-hand syndrome at stageⅠafter stroke were divided into the observation group and the control group according to the random number table method，60 cases in each group. The control group was given routine acupuncture combined with rehabilitation training，and the observation group was given Yangjing Jingjin Paici method combined with rehabilitation training. Both groups were treated for one month. The curative effect in the two groups was evaluated. Before and after treatment， the changes in range of motion of shoulder joint，the thickness of the palm，the scores of Fugl-Meyer Assessment(FMA) and Visual Analogue Scale (VAS)，and the levels of interleukin-6(IL-6)，high sensitive C-reactive protein(hs-CRP)，and tumor necrosis factor-α(TNF- α) in serum were observed in the two groups. The incidence of adverse reactions was recorded. Results：The total effective rate was 95.00% in the observation group，and 81.67% in the control group，the difference being significant(P＜0.05). After treatment， the range of anteflexion， posterior extension， adduction， abduction， pronation， and supination of shoulder joint were enlarged in the two groups(P＜0.05)； each index of range of motion of shoulder joint above in the observation group was higher than that in the control group(P＜0.05). After treatment，the thickness of the palm，the scores of FMA and VAS in the two groups were improved when compared with those before treatment(P＜0.05)； the improvement in the observation group were more significant than that in the control group(P＜0.05). After treatment，the levels of IL-6，hs-CRP and TNF-α in serum in the two groups were decreased when compared with those before treatment(P＜0.05)；the decrease in the observation group was more significant than that in the control group(P＜0.05). The incidence of adverse reactions was 3.33% in the observation group，and 5.00% in the control group；no significant difference was found in the comparison of the incidence between the two groups(P＞0.05). Conclusion：In the treatment of shoulder- hand syndrome at stageⅠafter stroke， the therapy of Yangjing Jingjin Paici method combined with rehabilitation training has significant curative effect， which can improve clinical symptoms and motor function of upper limbs， and reduce levels of inflammatory factors， with high safety.