Clinical Study on Western Medicine Combined with Bufei Zhiqiu Tang for Allergic Rhinitis with Lung-Spleen Qi Deficiency Syndrome
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摘要:
目的:观察西药联合补肺止鼽汤治疗变应性鼻炎(肺脾气虚证)的临床疗效。方法:将 90 例变应性鼻炎(肺脾气虚证)患者随机分为 3 组。西药组 30 例,予布地奈德鼻喷雾剂、氯雷他定片治疗;中药组 30 例,予自拟补肺止鼽汤治疗;观察组30 例,予布地奈德鼻喷雾剂、氯雷他定片及自拟补肺止鼽汤治疗。3 组均治疗 14 d 为 1 个疗程,疗程间停药休息 2 d,2 个疗程后比较 3 组的症状积分、体征积分、视觉模拟评分量表(VAS)评分变化、临床疗效情况。结果:与同组治疗前比较,治疗后3 组的症状积分、体征积分及 VAS 评分均明显下降 (P<0.01);与西药组治疗后比较,观察组 VAS 评分降低 (P<0.05);与中药组治疗后比较,观察组及西药组的症状积分、体征积分及 VAS 评分均降低,但差异无统计学意义 (P>0.05)。观察组临床疗效优于西药组及中药组(P<0.05);西药组与中药组临床疗效比较,差异无统计学意义(P>0.05)。结论:西药联合补肺止鼽汤可显著改善变应性鼻炎(肺脾气虚证)患者的临床症状体征,临床疗效虽稍优于西药组及中药组,但在改善症状、体征方面并不优于西药组及中药组,在降低 VAS 评分方面优于西药组,但并不优于中药组。
Abstract:
Abstract: Objective: To observe the clinical effect of western medicine combined with Bufei Zhiqiu tang for allergic rhinitis with lung- spleen qi deficiency syndrome. Methods:A total of 90 cases of patients with allergic rhinitis with lungspleen qi deficiency syndrome were randomly divided into three groups,30 cases in each group. The western medicine group was given budesonide nasal spray and loratadine tablets. The Chinese medicine group was given self-made Bufei Zhiqiu tang. The observation group was given budesonide nasal spray,loratadine tablets,and self-made Bufei Zhiqiu tang. The three groups were treated for two courses,14 days being one course,with two-day medicine withdrawal and rest between each course. After two courses,the changes in the scores of symptoms,signs and Visual Analogue Scale(VAS) as well as the clinical effect were compared among the three groups. Results: When compared with those in the same group before treatment,the scores of symptoms,signs,and VAS in the three groups after treatment were significantly decreased(P< 0.01). When compared with that in the western medicine group after treatment,the decrease in the score of VAS in the observation group was more obvious(P<0.05). When compared with those in the Chinese medicine group after treatment, the scores of symptoms,signs,and VAS in the observation group and the western medicine group were decreased,there being no significance in the difference(P>0.05). The clinical effect in the observation group was better than that in the western medicine group and the Chinese medicine group(P<0.05). No significant difference was found in the comparison of the clinical effect between the western medicine group and the Chinese medicine group(P>0.05). Conclusion:The therapy of western medicine combined with Bufei Zhiqiu tang can significantly improve clinical symptoms and signs of patients with allergic rhinitis with lung- spleen qi deficiency syndrome. Its clinical effect is slightly better than that in the western medicine group and the Chinese medicine group;but in terms of the improvement of symptoms and signs,this therapy shows no advantage when compared with the other two therapies. In terms of the decrease in score of VAS,the clinical effect of the therapy is better than that in the western medicine group,but is not superior to that in the Chinese medicine group.