Abstract：Objective：To discuss the effect of emotional nursing on anxiety and depression as well as quality of life in patients with gynecological tumor after chemotherapy. Methods：A total of 122 cases of patients with gynecological tumor were selected as the objects and divided into the control group and the experiment group based on coin tossing method， 61 cases in each group. The control group was given routine chemotherapy and nursing of gynecology，and the experiment group was additionally given emotional nursing based on the nursing of the control group. The scores of Self- rating Anxiety Scale(SAS)， Scale for measuring Satisfaction to Quality of Life， and Self- rating Depression Scale(SDS) were compared between the two groups so as to detect coefficients of anxiety and depression as well as quality of life. Results： After intervention，the scores of SAS and SDS in the two groups were improved when compared with those before intervention， and the two scores in the experiment group were lower than those in the control group，the difference being significant (P＜0.05). The satisfaction to quality of life in the experiment group was higher than that in the control group，the difference being significant between the two groups(P＜0.05). Conclusion： The additional emotional nursing can relieve anxiety and depression in patients with gynecological tumor，and improve their quality of life.