肾炎康复片联合雷公藤多苷片治疗肾小球肾炎临床及护理研究
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R692.3+1;R284

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Clinical and Nursing Study on Shenyan Kangfu Tablets Combined with Tripterygium Wilfordii Polyglycoside Tablets for Glomerulonephritis
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    摘要:

    目的:观察肾炎康复片联合雷公藤多苷片对肾小球肾炎患者临床及护理疗效。方法:将 110 例肾小球肾炎患者按随机数字表法分成 2 组,对照组 55 例患者采用雷公藤多苷片治疗,观察组 55 例患者采用肾炎康复片联合雷公藤多苷片治疗,再配合护理干预。对比 2 组患者干预后临床症状评分,干预前后肾功能指标、炎症指标。结果:干预后,观察组神疲乏力、尿频、腰肌酸痛、夜尿增多及浮肿纳呆等临床症状评分较对照组降低,差异有统计学意义 (P<0.05)。2 组干预前血肌酐、血浆白蛋白、尿素氮及 24 h 尿蛋白比较,差异无统计学意义 (P>0.05)。干预后,2 组各指标较前改善,观察组血肌酐、尿素氮及 24 h 尿蛋白较对照组降低,而血浆白蛋白则较对照组升高,差异有统计学意义(P<0.05)。2 组干预前 CRP、IL-13 及 TNF-α 比较,差异无统计学意义 (P>0.05)。干预后,2 组炎症指标较前改善,观察组 CRP、IL-13 及 TNF-α 较对照组降低,差异有统计学意义(P<0.05)。结论:肾小球肾炎应用肾炎康复片联合雷公藤多苷片治疗再配合护理干预,可有效改善临床症状,减轻其炎症反应,提高肾功能。

    Abstract:

    Abstract: Objective: To observe the clinical effect and nursing measures of Shenyan Kangfu tablets combined with tripterygium wilfordii polyglycoside tablets for patients with glomerulonephritis. Methods:A total of 110 cases of patients with glomerulonephritis were divided into two groups according to the random number table method,55 cases in each group. The control group was treated with tripterygium wilfordii polyglycoside tablets;the observation group was treated with Shenyan Kangfu tablets combined with tripterygium wilfordii polyglycoside tablets and then nursing intervention. Clinical symptom scores after intervention as well as the indexes of renal function and inflammation before and after intervention in the two groups were compared. Results:After intervention,the scores of clinical symptoms including lassitude of spirit and lack of strength,frequent micturition,aching pain in psoas,increased nocturia,and edema and torpid intake in the observation group were decreased when compared with those in the control group, the difference being significant(P<0.05). Before intervention,there was no significant difference being found in the comparison of serum creatinine,plasma albumin,urea nitrogen and 24 h urinary protein between the two groups(P>0.05);after intervention,the above indexes in the two groups were improved when compared with those before intervention;serum creatinine,urea nitrogen and 24 h urinary protein in the observation group were decreased when compared with those in the control group,and plasma albumin was increased, the difference being significant(P<0.05). Before intervention, there was no significant difference being found in the comparison of CRP,IL-13 and TNF-α between the two groups(P>0.05);after intervention,the inflammatory indexes in the two groups were improved,and CRP,IL-13 and TNF-α in the observation group were decreased when compared with those in the control group,the difference being significant(P<0.05). Conclusion:The application of Shenyan Kangfu tablets and tripterygium wilfordii polyglycoside tablets combined with nursing intervention for glomerulonephritis can effectively improve the clinical symptoms,reduce the inflammatory responses,and enhance the kidney function.

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罗佳.肾炎康复片联合雷公藤多苷片治疗肾小球肾炎临床及护理研究[J].新中医,2020,52(23):158-160

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  • 在线发布日期: 2020-12-09
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