Abstract： Objective： To observe the clinical nursing effect of auricular point pressing with beans combined with emotional nursing on intervening post-stroke depression(PSD). Methods：A total of 100 cases of PSD patients were randomly divided into the control group and the observation group，50 cases in each group. The control group was given flupentixol and melitracen tablets， nursing， health education and guidance， and psychological nursing measures. The observation group was additionally intervened with auricular point pressing with beans combined with emotional nursing based on the treatment of the control group. Both groups were treated for four weeks. The scores of Hamilton Depression Scale- 17(HAMD-17)， Zung Self- rating Depression Scale(SDS) and Zung Self- rating Anxiety Scale(SAS) before and after treatment were observed and compared between the two groups. The nursing satisfaction was evaluated when discharge. Results：After treatment， the depression degree of the observation group was lightor than that of the control and the difference was statistically significant(P＜0.05) The disappearance rate of depression was 76.00% in the observation group，and 52.00% in the control group，the difference being significant(P＜0.05). After treatment，the scores of HAMD，SAS and SDS in the two groups were significantly decreased when compared with those before treatment(P＜0.05)，and the three scores in the observation group were lower than those in the control group(P＜0.05). The nursing satisfaction in the observation group was better than that in the control group，the difference being significant(P＜0.05). Conclusion：Based on flupentixol and melitracen，namely auricular point pressing with beans combined with emotional nursing for PSD patients can reduce the degree of depression and anxiety，and effectively improve the disappearance rate of depression and clinical nursing satisfaction.