Abstract：Objective：To observe the clinical effect of short thrust needling for nerve root cervical spondylosis. Methods： A total of 76 cases of patients with nerve root cervical spondylosis were selected as the study subjects and divided into the control group and the observation group according to the random number table method， 36 and 40 cases in each group respectively. The control group was given routine acupuncture，and the observation group was given short thrust needling. After treatment for one month，the scores of Visual Analogue Scale (VAS)，36-Item Short Form Health Survey (SF-36) and Neck Disability Index(NDI)， the related indexes of inflammatory factors and the clinical effect in the two groups were compared. Results： After treatment， the scores of VAS and NDI in the two groups were decreased(P＜0.05)， and the decrease in the observation group was more significant， the difference being significant(P＜0.05). After treatment， the scores of each item in SF-36 in the two groups were increased(P＜0.05)；among them，the scores of body pain and social function in the observation group were higher than those in the control group，the difference being significant(P＜0.05). After treatment，the levels of interlenkin-1β(IL-1β) and tumor necrosis factor-α(TNF-α) in the two groups were decreased，and the decrease in the observation group was more significant，the difference being significant(P＜0.05). The total effective rate was 92.5% in the observation group，significantly higher than that of 75.0% in the control group(P＜0.05). Conclusion：Short thrust needling has definite curative effect in treating nerve root cervical spondylosis， and can better improve clinical symptoms and health，inhibit the development of inflammation and relieve pain.