Abstract：Objective：To observe the clinical effect of auricular point pressing with beans，Chinese herbal application and music therapy，based on the treatment of eszopiclone tablets and routine nursing measures，for mental illness complicated with sleep disorder. Methods： A total of 116 cases of patients were randomly divided into the control group and the observation group， 58 cases in each group. Both groups were given the oral administration of eszopiclone tablets and the intervention of routine nursing measures， and the observation group was additionally treated with auricular point pressing with beans，application with fructus evodiae powder at Yongquan point(KI1) and music therapy. Both groups were treated for six weeks. Before and after treatment for 6 weeks respectively， the total scores of Pittsburgh Sleep Quality Index(PSQI)， Insomnia Severity Index(ISI) and Fatigue Severity Scale(FSS) were assessed. The nursing satisfaction was evaluated at discharge. Results：After treatment，the clinical effect in the observation group was better than that in the control group(P＜ 0.05). The total scores of PSQI，ISI and FSS in the two groups were decreased when compared with those before treatment (P＜0.01)， and the total scores in the observation group were all lower than those in the control group(P＜0.01). Nursing satisfaction in the observation group was higher than that in the control group(P＜0.05). Conclusion：Based on the treatment of eszopiclone tablets and routine nursing measures，the intervention of auricular point pressing with beans，Chinese herbal application and music therapy for patients with mental illness complicated with sleep disorder can further reduce the degree of insomnia and fatigue as well as improve their quality of life，clinical effect and nursing satisfaction.