Abstract：Objective：To discuss the effect Chinese medicine nursing on scores of anxiety，depression and pain as well as nursing satisfaction in patients in ICU. Methods： A total of 104 cases of patients in ICU were divided into two groups according to the random number table method，52 cases in each group. The control group was given routine nursing，and the observation group was additionally given Chinese medicine nursing based on the treatment of the control group. Before and after nursing， the scores of Self- rating Depression Scale(SDS)， Self- rating Anxiety Scale(SAS)， Numerical Rating Scale (NRS)， and Critical- care Pain Observation Tool(CPOT)， as well as nursing satisfaction were compared between the two groups as well as nursing satisfaction. Results：After nursing，the scores of SDS and SAS in the two groups were improved when compared with those before nursing，and the two scores above in the observation group were lower than those in the control group，the difference being significant(P＜0.05). After nursing，the scores of NRS and CPOT in the two groups were improved when compared with those before nursing，and the two scores above in the observation group were lower than those in the control group， the difference being significant(P＜0.05). After nursing， nursing satisfaction in the observation group was better than that in the control group， the difference being significant(P＜0.05). Conclusion： Chinese medicine nursing can effectively relieve negative emotions including depression and anxiety of patients in ICU， significantly alleviate their pain，and effectively improve nursing satisfaction.