Abstract： Objective： To observe the clinical effect of Maxing Shigan tang combined with western medicine for pneumonic cough and asthma in children. Methods：A total of 74 cases of children with pneumonic cough and asthma were divided into the western medicine group and the integrated Chinese and western medicine group according to the random number table method，37 cases in each group. The western medicine group was given antibacterial and antiviral treatment according to the disease conditions，and the integrated Chinese and western medicine group was additionally treated with Maxing Shigan tang based on the treatment of the western medicine group. The total effective rates of clinical treatment in the two groups were compared. Before and after treatment，the Chinese medicine syndrome scores，the disappearance time of clinical symptoms and the incidences of adverse reactions in the two groups were observed. Results：The total effective rate was 94.59% in the integrated Chinese and western medicine group and 81.08% in the western medicine group， the difference being significant(P<0.05). After treatment， the Chinese medicine syndrome scores of main and secondary symptoms in the two groups were decreased when compared with those before treatment(P＜0.05)，and the scores in the integrated Chinese and western medicine group were lower than those in the western medicine group(P＜0.05). The recovery time of body temperature and the disappearance time of coughing，wheezing and pulmonary rales in the integrated Chinese and western medicine group were earlier than those in the western medicine group，the difference being significant(P＜0.05). The incidence of adverse reactions was 5.41% in the integrated Chinese and western medicine group， and 2.70% in the western medicine group；there was no significant difference between the two groups(P＞0.05). Conclusion：The therapy of Maxing Shigan tang combined with western medicine for children with pneumonic cough and asthma can significantly improve their clinical symptoms and the total effective rates of treatment.