Abstract：Objective：To observe the clinical effect of Congrong Tongbian oral liquid on Geriatric constipation. Methods： A total of 78 cases with Geriatric constipation were divided into the control group and the treatment group according to the random number table method， 39 cases in each group. The control group was simply treated with Mosapride， and the treatment group was additionally treated with Congrong Tongbian oral liquid based on the treatment of the control group. The clinical effect，therapeutic effect of different levels of constipation and adverse reactions were compared between the two groups. Results：The total effective rate was 94.87% in the treatment group and 79.49% in the control group，the difference being significant(P＜0.05). The therapeutic effect of different levels of constipation in the treatment group was better than that in the control group，the difference being significant(P＜0.05). The incidence of adverse reactions was 20.51% in the control group and 5.13% in the treatment group， the difference being significant(P＜0.05). Conclusion： Congrong Tongbian oral liquid has a significant therapeutic effect on patients with Geriatric constipation，which can significantly relieve the clinical symptoms and reduce the clinical adverse reactions.