Abstract： Objective： To observe the effect of Kangfuxin liquid， compound Tongye burn oil combined with negative pressure suction for wound healing of burn. Methods：A total of 73 cases of patients with burn were selected as the study subjects and randomly divided into the observation group and the control group，37 and 36 cases in each group respectively. The control group was treated with traditional methods， and the observation group was treated with Kangfuxin liquid， compound Tongye burn oil combined with negative pressure suction. The differences of treatment and curative effect in the two groups were compared. Results：The wound healing time in the observation group was shorter than that in the control group，and the average times of dressing change were fewer，the difference being significant(P＜0.05). The total effective rate of treatment was 100% in the observation group，higher than that of 88.89% in the control group，the difference being significant(P＜0.05). Conclusion： The application of Kangfuxin liquid， compound Tongye burn oil combined with negative pressure suction can significantly shorten the wound healing time of patients， reduce the times of dressing change， effectively improve clinical effect and decrease the economic burden.