Abstract： Objective： To observe the clinical effect of point application assisting modified Shugan Jieyu capsules and Huanglian Ejiao tang for coronary heart disease angina complicated with depression of non-interaction between the heart and kidney type. Methods：A total of 62 cases of patients with coronary heart disease angina complicated with depression were divided into the control group and the observation group according to the random number table method， 31 cases in each group. Both groups were given routine treatment for coronary heart disease； the control group was additionally given modified treatment of Shugan Jieyu capsules and Huanglian Ejiao tang，and the observation group was additionally treated with point application based on the treatment of the control group. The clinical effect and the scores of Hamilton Depression Scale(HAMD- 17)， Self- Rating Depression Scale(SDS)， Symptom Checklist- 90(SCL- 90) and Beck Depression Inventory (BDI) in the two groups were compared. Results：The total effective rate was 93.55% in the observation group，higher than that of 67.74% in the control group， the difference being significant(P＜0.05). Before treatment， there was no significant difference being found in the comparison of the scores of HAMD- 17， SDS， SCL- 90 and BDI between the two groups (P＞0.05). After treatment， the scores of HAMD- 17， SDS， SCL- 90 and BDI in the two groups were decreased when compared with those before treatment，and the scores in the observation group were lower than those in the control group (P＜0.05). Conclusion：The treatment of point application assisting modified Shugan Jieyu capsules and Huanglian Ejiao tang has better clinical effect in treating coronary heart disease angina complicated with depression of non-interaction between the heart and kidney type，which can improve the depressive symptoms of patients.