麝香保心丸联合替格瑞洛治疗冠心病不稳定型心绞痛临床研究
DOI:
CSTR:
作者:
作者单位:

作者简介:

通讯作者:

中图分类号:

R541.4

基金项目:


Clinical Study on Shexiang Baoxin Pils Combined with Ticagrelor for Unstable Angina Pectoris of Coronary Heart Disease
Author:
Affiliation:

Fund Project:

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 资源附件
  • |
  • 文章评论
    摘要:

    目的:观察麝香保心丸联合替格瑞洛治疗冠心病不稳定型心绞痛的临床疗效。方法:选取冠心病不稳定型心绞痛患者 68 例,按随机数字表法分为对照组和观察组各 34 例。2 组均给予西医常规治疗,对照组给予替格瑞洛片治疗,观察组在对照组基础上给予麝香保心丸口服。比较 2 组心绞痛发作、临床疗效、生活质量西雅图心绞痛量表(SAQ)评分。结果:观察组总有效率为 91.18%,对照组为 67.65%,2 组比较,差异有统计学意义 (P<0.05)。治疗前,2 组 SAQ 指标各项评分比较,差异均无统计学意义 (P>0.05)。治疗后,2 组 SAQ 指标各项评分较治疗前升高,且观察组 SAQ 指标各项评分均高于对照组,差异均有统计学意义 (P<0.05)。治疗前,2 组每周心绞痛发作次数、每周硝酸甘油用量、每次持续时间比较,差异均无统计学意义(P>0.05)。治疗后,2 组每周心绞痛发作次数、每周硝酸甘油用量、每次持续时间较治疗前下降,且观察组各项指标均低于对照组,差异均有统计学意义(P<0.05)。结论:麝香保心丸联合替格瑞洛治疗冠心病不稳定型心绞痛的疗效确切,可以降低心绞痛发作次数和硝酸甘油用量,提高患者生活质量。 [关键词] 冠心病不稳定型心绞痛;麝香保心丸

    Abstract:

    Abstract:Objective:To observe the clinical effect of Shexiang Baoxin pills combined with ticagrelor for unstable angina pectoris of coronary heart disease. Methods:A total of 68 cases of patients with unstable angina pectoris of coronary heart disease were selected and divided into the control group and the observation group according to the random number table method, 34 cases in each group. Both groups were given routine western medicine treatment; the control group was additionally given ticagrelor,and the observation group was additionally given the oral administration of Shexiang Baoxin pills based on the treatment of the control group. Angina pectoris seizure, clinical effect, and score of Seattle Angina Questionnaire(SAQ) were compared between the two groups. Results:The total effective rate was 91.18% in the observation group,and 67.65% in the control group,the difference being significant(P<0.05). When compared each score of SAQ index between the two groups,there was no significance in differences(P>0.05). After treatment,each score of SAQ index in the two groups was increased when compared with that before treatment,and the scores in the observation group were higher than those in the control group,differences being significant(P<0.05). Before treatment,when compared frequency of angina pectoris seizure each week,nitroglycerin dosage each week,and duration of seizure each time between the two groups,there was no significance in differences(P>0.05). After treatment,frequency of angina pectoris seizure each week,nitroglycerin dosage each week,and duration of seizure each time in the two groups were decreased when compared with those before treatment,and each index in the observation group was lower than that in the control group, differences being significant(P<0.05). Conclusion:In the treatment of unstable angina pectoris of coronary heart disease, the therapy of Shexiang Baoxin pills combined with ticagrelor has defined curative effect, which can lower frequency of angina pectoris seizure and nitroglycerin dosage,and improve quality of life.

    参考文献
    相似文献
    引证文献
引用本文

周丹,张治平.麝香保心丸联合替格瑞洛治疗冠心病不稳定型心绞痛临床研究[J].新中医,2021,53(7):61-63

复制
分享
文章指标
  • 点击次数:
  • 下载次数:
  • HTML阅读次数:
  • 引用次数:
历史
  • 收稿日期:
  • 最后修改日期:
  • 录用日期:
  • 在线发布日期: 2021-04-08
  • 出版日期:
文章二维码