Abstract： Objective： To explore the administration rule of prescriptions by Prof. XIONG Monian， a famous Chinese medicine practitioner for tumor in Jiangxi Province，so as to promote the better implementation of the inheritance of famous practitioners and to guide the clinical practice. Methods：A total of 353 prescriptions were collected from 59 patients with breast cancer admitted to Prof. XIONG's outpatient department. The characteristics of administration rule of these prescriptions were excavated through the Chinese Medicine Inheritance Assistant Platform， and then were analyzed. Results：In terms of the four natures，prescriptions were cold and heat. In terms of the five flavors，prescriptions were mainly sweet，followed by bitter and acrid. In terms of meridian entry，prescriptions were mainly from the liver，spleen and lung meridians. The commonly used herbs were Rhizoma Atractylodis Macrocephalae， Radix et Rhizoma Glycyrrhizae， Cymbidium faberi Rolfe，Herba Hedyotis Diffusae，Herba Scutellariae Barbatae，Radix et Rhizoma Ginseng Cruda，Rhizoma Paridis， Polyporus Frondosus， Rhizoma Fagopyri Dibotryis， Radix Angelicae Sinensis， Xiaojie powder， Cordyceps sobolifer，Radix Astragali，Radix Bupleuri，Carapax Trionycis and Caulis Polygoni Multiflori. Conclusion：Prof. XIONG takes the principle of tonifying qi and clearing toxin when treating breast cancer，and the main herbs are of qi- tonifying， heatclearing and detoxifying type. While using qi-tonifying herbs，his administration is often combined with Rhizoma Atractylodis Macrocephalae to strengthen the spleen and tonify qi，focusing on regulating the spleen and stomach qi；and heat-clearing and detoxifying herbs are chosen from those who have been proved to have certain anti- tumor effect based on the characteristics of breast cancer with combination of the results of pharmacological studies of modern medicine. Meanwhile， qi- regulating herbs like Radix Bupleuri，Pericarpium Citri Reticulatae，Radix Aucklandiae and Rhizoma Cyperi are taken into consideration to enter the liver meridian according to the physiological characteristics of female breasts.