Abstract：Objective：To observe the effect of enema with Jiedu Huazheng tang combined with routine western medicine on levels of T- lymphocyte subsets and hypersensitivity C- reaction protein(hs- CRP) in serum as well as Chinese medicine syndrome of patients with pelvic inflammatory mass with dampness- heat accumulation syndrome. Methods： A total of 90 cases of patients with pelvic inflammatory mass with dampness-heat accumulation syndrome were selected，and divided into the experiment group and the control group according to the random number table method，45 cases in each group. The control group was given injection of ceftriaxone sodium and ornidazole injection，and the experiment group was additionally given enema with Jiedu Huazheng tang based on the treatment of the control group. Indexes of T- lymphocyte subsets and level of hs- CRP in serum， as well as Chinese medicine syndrome scores before and after treatment were compared between the two groups. Results： After treatment， levels of hs- CRP in serum in the two groups were decreased when compared with those before treatment(P＜0.05)，and the level in serum in the experiment group was lower than that in the control group(P＜0.05). After treatment，levels of CD3 +，CD4 +，and CD8 + in serum as well as CD4 +/CD8 + ratio in the two groups were improved when compared with those before treatment(P＜0.05)；levels of CD3+ and CD4+ in serum as well as CD4+/CD8+ ratio in the experiment group were higher than those in the control group(P＜0.05)，and levels of CD8+ in serum were lower(P＜0.05). After treatment，scores of lassitude of spirit and lack of strength，lower abdominal pain，low grade fever， and distending pain in the lumbosacral spine in the two groups were decreased when compared with those before treatment(P＜0.05)，and the four Chinese medicine syndrome scores above in the experiment group were lower than those in the control group(P＜0.05). Conclusion： For patients with pelvic inflammatory mass with dampness- heat accumulation syndrom， enema with Jiedu Huazheng tang can conduce to improving levels of T lymphocytes subsets and hs- CRP in serum，and decrease Chinese medicine syndrome scores.