Abstract：Objective：To observe the application effect of concentrated Dachengqi tang in senile patients with cancerrelated incomplete intestinal obstruction. Methods： A total of 80 cases of senile patients with cancer- related incomplete intestinal obstruction were divided into the control group and the observation group according to the random number table method，40 cases in each group. Based on routine treatment，the control group was additionally given retention enema with 200 mL of Dachengqi tang， and the observation group was additionally given retention enema with 50 mL of Dachengqi tang，twice a day for 2 weeks. The clinical effect，the improvement time of main symptoms and the drug retention time in the two groups were compared；the changes in gas-liquid plane of intestinal tube and intestinal pneumatosis in abdominal X- ray plain film were observed； the levels of inflammatory factors including procalcitonin(PCT)， tumor necrosis factor- α (TNF- α) and interleukin- 8(IL- 8) in serum were measured. Results：The total effective rate was 97.50% in the observation group and 87.50% in the control group， there being no significance in the difference(P＞0.05). After treatment， the anal exhaust time，the defecation time，the disappearance time of abdominal pain and abdominal distention and the recovery time of bowel sounds in the observation group were significantly shortened when compared with those in the control group，and the drug retention time was significantly prolonged(P＜0.05). After treatment，the improvement of abdominal X-ray plain film in the observation group was better than that in the control group，and the disappearance of gas-liquid plane of intestinal tube and the reduction of intestinal pneumatosis were significantly more(P＜0.05). Before treatment， there was no significant difference being found in the comparison of levels of PCT， TNF- α and IL- 8 between the two groups(P＞0.05). After treatment， the levels of PCT， TNF- α and IL- 8 in the two groups were decreased when compared with those before treatment， and the above levels in the observation group were lower than those in the control group， differences being significant(P＞0.05). Conclusion： The concentrated Dachengqi tang has better clinical effect in the treatment of senile patients with cancer-related incomplete intestinal obstruction，which is more conducive to improving the clinical symptoms of patients， prolonged the drug retention time， promoting the recovery of gastrointestinal function and reducing the inflammatory response of the body.