Abstract： Objective： To observe the curative effect of Chinese medicine hot compress combined with manipulation release for scapulohumeral periarthritis. Methods：A total of 58 cases of patients with scapulohumeral periarthritis were given retrospective analysis and divided into the observation group and the control group according to different treatment methods， 29 cases in each group．The control group was treated with manipulation release，and the observation group was additionally treated with Chinese medicine hot compress based on the treatment of the control group． The degree of shoulder pain， shoulder joint function and shoulder activities before and after treatment as well as the clinical effect in the two groups were compared. Results：The total effective rate was 96.55% in the observation group，significantly higher than that of 68.97% in the control group， the difference being significant(P＜0.05)． Before treatment， there was no significant difference being found in the comparison of Visual Analogue Scale(VAS) scores between the two groups(P＞0.05). After treatment， VAS scores in the two groups were decreased when compared with those before treatment，and the VAS score in the observation group was significantly lower than that in the control group， the difference being significant(P＜0.05)． Before treatment， there was no significant difference being found in the comparison of the shoulder function classification and the University of California， Los Angeles(UCLA) Shoulder Score between the two groups(P＞0.05)． After treatment， the shoulder function classification and the UCLA Shoulder Score in the two groups were improved when compared with those before treatment， and the improvement in the observation group was better than that in the control group， differences being significant(P＜ 0.05). Before treatment，there was no significant difference being found in the comparison of angles of extorsion，abduction and uplift in the arms between the two groups(P＞0.05)．After treatment，the angles of extorsion，abduction and uplift in the arms in the two groups were increased when compared with those before treatment， and the above angles in the observation group were higher than those in the control group，differences being significant(P＜0.05)．Conclusion：Chinese medicine hot compress combined with manipulation release has significant curative effect for patients with scapulohumeral periarthritis，which can improve the degree of shoulder pain and shoulder activities，and recover the shoulder joint function.