Abstract： Objective： To discuss correlation between Chinese medicine constitutions of patients with early diabetic nephropathy and Chinese medicine syndromes. Methods： A total of 300 cases of patients with early diabetic nephropathy were enrolled in the study group. Another 300 cases of patients with type 2 diabetes and without diabetic nephropathy were enrolled in the control group. In the two groups，distribution of Chinese medicine constitution types and Chinese medicine syndromes was counted. Among the patients of different Chinese medicine constitution types in the study group， the distribution of Chinese medicine syndromes was counted. The correlation between Chinese medicine constitutions and Chinese medicine syndromes in the study group was analyzed. Results：In the study group，the proportions of qi-deficiency constitution and blood stasis constitution were larger than those in the control group(P＜0.01)， and the proportions of balanced constitution and yang- deficiency constitution were lower(P＜0.01). When compared the distribution of yindeficiency constitution， phlegm- dampness constitution， dampness- heat constitution， qi- depression constitution， and special intrinsic constitution between the two groups，there was no significance being found in differences(P＞0.05). In the study group，the proportions of qi-deficiency syndrome，yin-deficiency syndrome，and blood stasis syndrome were larger than those in the control group(P＜0.05，P＜0.01)，and the proportion of yang-deficiency syndrome was lower than that in the control group(P＜0.01). When compared the distribution of water-dampness syndrome，dampness-heat syndrome，and dampness- turbidity syndrome between the two groups， there was no significance being found in differences(P＞0.05). Among the patients with different constitutions in the study group，patients with qi-deficiency constitution were more likely to show qi- deficiency syndrome and yin- deficiency syndrome； patients with yin- deficiency constitution showed qideficiency syndrome and yin- deficiency syndrome； patients with blood stasis constitution were more likely to show qideficiency syndrome and blood stasis syndrome；patients with balanced constitution were more likely to show qi-deficiency syndrome and yang- deficiency syndrome；patients with phlegm- dampness constitution were more likely to show waterdampness syndrome；patients with dampness- heat constitution showed dampness- heat syndrome and water- dampness syndrome；patients with qi- depression constitution were more likely to show blood stasis syndrome；patients with yangdeficiency constitution showed yang-deficiency syndrome and qi-deficiency syndrome. Qi-deficiency constitution and yindeficiency constitution were strongly correlated with qi- deficiency syndrome and yin- deficiency syndrome； phlegmdampness constitution was strongly correlated with water-dampness syndrome，and moderately correlated with dampnessheat syndrome；dampness- heat constitution had a moderate correlation with water- dampness syndrome and dampnessheat syndrome；blood stasis constitution was strongly correlated with qi- deficiency syndrome，and moderately correlated with blood stasis syndrome；there was a strong correlation between qi-depression constitution and blood stasis syndrome. Conclusion：Diabetes patients with qi-deficiency constitution and blood stasis constitution are more likely to be susceptible to early diabetic nephropathy. There is certain correlation between Chinese medicine syndromes and Chinese medicine constitutions， and constitution types may determine characteristics of Chinese medicine syndromes at the onset of the disease and after it in diabetes patients.