Abstract：Objective：To observe the clinical effect of Tongfu Huayu tang and acupuncture combined with rehabilitation training for ischemic stroke. Methods：A total of 90 cases of patients with ischemic stroke were selected and divided into the control group and the observation group according to the random number table method，45 cases in each group. Both groups were given routine western medicine； the control group was additionally treated with Tongfu Huayu tang combined with acupuncture， and the observation group was additionally treated with rehabilitation training based on the treatment of the control group. Both groups were treated for two months. The scores of National Institute of Health Stroke Scale (NIHSS)， Chinese Stroke Scale (CSS)， Fugl- Meyer Assessment (FMA)， Barthel index (BI) and Generic Quality of Life Inventory- 74 (GQOLI- 74) before and after treatment and the clinical effect in the two groups were compared. Results：After treatment， the scores of NIHSS and CSS in the observation group were lower than those in the control group，and the scores of FMA and BI were higher(P＜0.05). After treatment，the scores of physical function，mental function，social function and material life in the observation group were higher than those in the control group(P＜0.05). The total effective rate was 95.56% in the observation group， higher than that of 82.22% in the control group(P＜0.05). Conclusion： Tongfu Huayu tang and acupuncture combined with rehabilitation training for ischemic stroke can improve the neurological deficit of patients and their quality of life，and promote the recovery of motor function of limbs.