Abstract：Objective：To observe the clinical effect of Shugan Tiaoshen needling method of acupuncture for generalized anxiety. Methods：A total of 84 cases of patients with generalized anxiety were divided into the observation group and the control group according to the random number table method，42 cases in each group. The control group was given western medicine，which was paroxetine. The observation group was given acupuncture of Shugan Tiaoshen needling method. After treatment，the clinical effect was evaluated in the two groups. Results：After treatment，the total clinical effective rate was 90.48% in the observation group，better than that of 71.43% in the control group，the difference being significant(P＜0.05). Before treatment，when compared scores of Hamilton Anxiety Scale(HAMA) and Self-rating Anxiety Scale(SAS) between the two groups，there was no significance being found in the difference(P＞0.05). After one-week，two-week，and four-week treatment， scores of HAMA and SAS in the two groups were decreased in different degrees when compared with those before treatment(P＜0.05)，and the two scores in the observation group were lower than those in the control group(P＜0.05). Before treatment，when compared the scores of all dimensions in SF-36 and the total score between the two groups，there was no significance being found in the difference(P＞0.05). After treatment，the scores of all dimensions in SF- 36 and the total score in the two groups were significantly increased，and the increase in the observation group was significantly better than that in the control group(P＜0.05). Conclusion： Acupuncture of Shugan Tiaoshen needling method has satisfactory curative effect on generalized anxiety，which conduces to relieving anxiety symptoms and improving quality of life.