Abstract：Objective：To observe the effect of Chinese medicine comprehensive nursing on emotions and quality of life in patients with anxiety undergoing urology surgery. Methods：A total of 110 cases of patients with anxiety undergoing urology surgery were divided into the control group and the observation group according to the random number table method ， 55 cases in each group. The control group was given routine nursing，and the observation group was additionally intervened with Chinese medicine comprehensive nursing based on the treatment of the control group. The scores of Self-rating Anxiety Scale(SAS) and Quality of Life Questionnaire(QLQ-C30) as well as the nursing satisfaction in the two groups were compared. Results：On admission，there was no significant difference being found in the comparison of the SAS scores between the two groups(P＞0.05). 14 days after surgery， the SAS scores in the two groups were lower than those on admission(P＜ 0.05)，and the SAS score in the observation group was lower than that in the control group(P＜0.05). On admission，there was no significant difference being found in the comparison of each score and the total scores in QLQ-C30 between the two groups(P＞0.05). 14 days after surgery，each score and the total scores in QLQ-C30 in the two groups were increased when compared with those on admission(P＜0.05)，and the above scores in the observation group were higher than those in the control group(P＜0.05). The nursing satisfaction was 94.55% in the observation group and 80.00% in the control group，the difference being significant(P＜0.05). Conclusion： Based on routine nursing， the intervention of Chinese medicine comprehensive nursing for patients with anxiety undergoing urology surgery can significantly improve their anxiety，quality of life and nursing satisfaction.