Abstract： Objective： To observe the clinical effect of Xiaoqinglong tang and point application combined with routine therapy for acute exacerbation of chronic obstructive pulmonary disease(AECOPD). Methods：A total of 76 cases of AECOPD patients of exterior cold with interior fluid retention type were divided into the treatment group and the control group according to the random number table method， 38 cases in each group. Both groups were given modern medical comprehensive treatment including oxygen inhalation，anti-infection，anti-inflammation and bronchodilation，and the treatment group was additionally given the oral administration of Xiaoqinglong tang and treated with point application. Both groups were treated for 14 days. The clinical effect in the two groups was compared. Before treatment and after 14 days of treatment，the changes of Chinese medicine symptom scores and indexes of blood gas analysis[arterial partial pressure of oxygen(PaO2) and partial pressure of carbon dioxide(PaCO2)] and lung function[the percentage of forced expiratory volume in one second to the predicted value(FEV1%) and the percentage of FEV1 to forced vital capacity(FEV1/FVC%)]were observed. Results：After 14 days of treatment，the total effective rate was 89.5% in the treatment group and 65.8% in the control group，the difference being significant(P＜0.01). The scores of coughing，expectoration，gasp，wheezing and cyanosis as well as the total scores in the two groups were decreased when compared with those before treatment(P＜0.05），and the above scores in the treatment group were lower than those in the control group(P＜0.05). The PaO2 in the two groups were increased when compared with those before treatment，and the PaCO2 were decreased(P＜0.05). PaO2 in the treatment group was higher than that in the control group(P＜0.05)， and PaCO2 was lower(P＜0.05). FEV1/FVC% and FEV1% in the two groups were increased when compared with those before treatment(P＜0.05). FEV1/FVC% and FEV1% in the treatment group were higher than those in the control group(P＜0.05). Conclusion： Based on modern medical routine therapy， the additional application of Xiaoqinglong tang combined with point application can effectively improve the clinical effect of AECOPD patients and improve their lung function，which has better curative effect than single modern medical therapy.