益气复脉汤加减联合美托洛尔治疗气阴两虚证冠心病心律失常临床研究
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R541.4

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Clinical Study on Modified Yiqi Fumai Tang Combined with Metoprolol for Arrhythmia in Coronary Heart Disease with Syndrome of Dual Deficiency of Qi and Yin
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    摘要:

    目的:观察益气复脉汤加减联合琥珀酸美托洛尔缓释片治疗气阴两虚证冠心病心律失常的临床疗效。方法:将气阴两虚证冠心病心律失常患者105 例随机分为对照组54 例与治疗组51 例。对照组给予常规基础治疗联合琥珀酸美托洛尔缓释片口服,治疗组在对照组的基础上加用益气复脉汤加减治疗。2 组均连续治疗3 个月,比较2 组临床疗效,评定2 组治疗前后中医症状积分,同时采用匹兹堡睡眠质量指数量表(PSQI) 评价患者的睡眠质量。结果:治疗组总有效率为90.20%,对照组为70.37%,2 组比较,差异有统计学意义(P<0.05)。治疗前,2 组心悸、气短、乏力、心烦失眠、盗汗等中医症状积分及总分比较,差异无统计学意义(P>0.05);治疗后,2 组上述各项积分及总分均较治疗前降低(P<0.05),且治疗组各项积分及总分均较对照组低(P<0.05)。治疗前,2 组PSQI 评分比较,差异无统计学意义(P>0.05);治疗后,2 组PSQI 评分均较治疗前降低(P<0.05),且治疗组PSQI 评分低于对照组(P<0.05)。结论:益气复脉汤加减联合美托洛尔治疗气阴两虚证冠心病心律失常能提高临床疗效,显著改善患者的临床症状及睡眠质量。

    Abstract:

    Abstract: Objective: To observe the clinical effect of modified Yiqi Fumai tang combined with metoprolol succinate sustained-release tablets for arrhythmia in coronary heart disease with syndrome of dual deficiency of qi and yin. Methods:A total of 105 cases of patients with arrhythmia in coronary heart disease with syndrome of dual deficiency of qi and yin were randomly divided into the control group and the treatment group, 54 and 51 cases in each group respectively. The control group was given routine basic treatment combined with oral administration of metoprolol succinate sustained- release tablets,and the treatment group was additionally traeted with modified Yiqi Fumai tang based on the treatment of the control group. Both groups were treated for three months. The clinical effect in the two groups was compared;the Chinese medicine symptom scores in the two groups before and after treatment were evaluated;the sleep quality of patients was assessed by Pittsburgh Sleep Quality Index(PSQI). Results:The total effective rate was 90.20% in the treatment group and 70.37% in the control group,the difference being significant(P<0.05). Before treatment,there was no significant difference being found in the comparison of the Chinese medicine symptom scores including palpitation,shortness of breath,fatigue,vexation and insomnia, and night sweating as well as the total scores between the two groups(P>0.05); after treatment, the above scores and the total scores in the two groups were decreased when compared with those before treatment(P<0.05),and the above scores the total score in the treatment group were lower than those in the control group(P<0.05). Before treatment, there was no significant difference being found in the comparison of the PSQI scores between the two groups(P>0.05);after treatment,the PSQI scores in the two groups were decreased when compared with those before treatment(P<0.05),and the PSQI score in the treatment group was lower than that in the control group(P<0.05). Conclusion:Modified Yiqi Fumai tang combined with metoprolol can improve the clinical effect in treating arrhythmia in coronary heart disease with syndrome of dual deficiency of qi and yin,which can significantly improve the clinical symptoms and the sleep quality of patients.

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任琳琳.益气复脉汤加减联合美托洛尔治疗气阴两虚证冠心病心律失常临床研究[J].新中医,2021,53(13):68-71

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  • 在线发布日期: 2021-07-11
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