七福饮加味治疗轻中度血管性痴呆肾虚髓减证临床研究
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R749.13

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Clinical Study on Modified Qifu Yin for Mild- to- Moderate Vascular Dementia with Syndrome of Kidney Deficiency and Marrow Depletion
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    摘要:

    目的:观察七福饮加味对轻中度血管性痴呆(VD) 肾虚髓减证的治疗效果。方法:选取轻中度VD 患者70 例,按随机数字表法分为观察组和对照组,各35 例。2 组均予常规治疗,对照组加用吡拉西坦注射液,观察组在对照组基础上予七福饮加味治疗。治疗3 个月后,比较2 组的认知能力、中医证候积分,评估2 组治疗效果。结果:与同组治疗前比较,2 组治疗后简易精神状态检查(MMSE)、蒙特利尔认知评估量表(MoCA) 评分均升高(P<0.05),智能减退、腰膝酸软、倦怠思卧等中医证候积分均下降(P<0.05);与对照组治疗后比较,观察组治疗后MMSE、MoCA 评分均较高(P<0.05),智能减退、腰膝酸软、倦怠思卧等中医证候积分均较低(P<0.05)。治疗后,观察组总有效率为91.43%,高于对照组的68.57% (P<0.05)。结论:七福饮加味治疗轻中度VD 髓海不足证疗效明显,能改善认识功能和髓海不足证的主症。

    Abstract:

    Abstract: Objective: To observe the curative effect of modified Qifu yin on mild- to- moderate vascular dementia(VD) with syndrome of kidney deficiency and marrow depletion. Methods:A total of 70 cases of patients with mild-to-moderate VD were selected and divided into the observation group and the control group according to the random number table method, 35 cases in each group. Both groups were given routine treatment; the control group was additionally given piracetam injection,and the observation group was additionally given modified Qifu yin based on the treatment of the control group. After three- month treatment,cognitive ability and Chinese medicine syndrome score were compared between the two groups. The curative effect was evaluated in the two groups. Results:When compared with those before treatment in the same group, scores of Mini mental state(MMSE) and Montreal Cognitive Assessment(MoCA) in the two groups were increased after treatment(P<0.05), and the Chinese medicine syndrome scores of intelligence decline, soreness and weakness of the waist and knees,fatigue,and a desire for lying down were decreased(P<0.05). After treatment,scores of MMSE and MoCA in the observation group were higher than those in the control group(P<0.05),and the Chinese medicine syndrome scores of intelligence decline, soreness and weakness of the waist and knees, fatigue, and a desire for lying down were lower(P<0.05). After treatment,the total effective rate was 91.43% in the observation group,higher than that of 68.57% in the control group(P<0.05). Conclusion:Modified Qifu yin has a significant curative effect on mild- to- moderate VD with sea of marrow depletion syndrome, which can improve cognitive function and main symptoms of sea of marrow depletion syndrome.

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王位,刘茜茜.七福饮加味治疗轻中度血管性痴呆肾虚髓减证临床研究[J].新中医,2021,53(14):46-48

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  • 在线发布日期: 2021-07-24
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