Abstract： Objective： To observe the effect of emotional nursing combined with rehabilitation nursing on negative emotions and compliance in senile patients with cerebral infarction. Methods： A total of 94 cases of senile patients with cerebral infarction were divided into the control group and the observation group according to the random number table method，47 cases in each group. The control group was given routine basic nursing measures，and the observation group was additionally given emotional nursing combined with rehabilitation nursing based on the treatment of the control group. Both groups were intervened for two months. The scores of Self-rating Anxiety Scale(SAS) and Self-rating Depressing Scale (SDS) before and after treatment and the compliance and satisfaction in patients in the two groups were compared. Results： Before nursing，there was no significant difference being found in the comparison of scores of SAS and SDS(P＞0.05). After nursing，the scores of SAS and SDS in the two groups were decreased when compared with those before nursing(P＜0.05)， and the scores in the observation group were lower than those in the control group(P＜0.05). Before nursing，there was no significant difference being found in the comparison of the scores of compliance for rehabilitative exercise， life styles and drug administration between the two groups. After nursing，the scores of compliance for rehabilitative exercise，life styles and drug administration in the two groups were increased when compared with those before nursing(P＜0.05)， and the scores in the observation group were higher than those in the control group(P＜0.05). The nursing satisfaction rate was 97.87% in the observation group and 80.85% in the control group， the difference being significant(P＜0.05). Conclusion： Emotional nursing combined with rehabilitation nursing for senile patients with cerebral infarction can effectively improve their anxiety and depression，treatment compliance and nursing satisfaction.