芪苈强心胶囊联合常规西药治疗缺血性心肌病伴心力衰竭临床研究
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R541.4

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Clinical Study on Qili Qiangxin Capsules Combined with Routine Western Medicine for Ischemic Cardiomyopathy Complicated with Heart Failure
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    摘要:

    目的:观察芪苈强心胶囊联合常规西药治疗缺血性心肌病(ICM) 伴心力衰竭的临床疗效。方法:将ICM 伴心力衰竭患者232 例随机分为治疗组和对照组各116 例,对照组采用常规西药治疗,治疗组在对照组的基础上加用芪苈强心胶囊治疗。2 组均持续治疗3 个月,观察比较2 组临床疗效及治疗前后中医证候积分;测定2 组治疗前后心室重构指标,包括左室舒张末期内径(LVEDD)、左室收缩末期内径(LVESD)、左室射血分数(LVEF)。结果:治疗组总有效率为97.41%, 对照组为88.79%,2 组比较,差异有统计学意义(P<0.05)。治疗后,2 组中医证候积分均较治疗前降低(P<0.05),且治疗组中医证候积分低于对照组(P<0.05)。治疗后,2 组LVEDD、LVESD 水平均较治疗前降低(P<0.05),LVEF 水平均较治疗前升高(P<0.05);且治疗组各项指标改善均较对照组更显著(P<0.05)。结论:芪苈强心胶囊联合常规西药治疗ICM 伴心力衰竭具有良好疗效,能够有效改善心室重构,缓解患者临床症状。

    Abstract:

    Abstract:Objective:To observe the clinical effect of Qili Qiangxin capsules combined with routine western medicine for ischemic cardiomyopathy(ICM) complicated with heart failure. Methods: A total of 232 cases of ICM patients complicated with heart failure were randomly divided into the treatment group and the control group,116 cases in each group. The control group was given routine western medicine treatment method, and the treatment group was additionally treated with Qili Qiangxin capsules based on the treatment of the control group. Both groups were treated for three months. Chinese medicine syndrome scores before and after treatment and the clinical effect in the two groups were observed and compared. Before and after treatment, the indexes of ventricular remodeling including left ventricular end diastolic diameter(LVEDD), left ventricular end- systolic dimension(LVESD) and left ventricular ejection fraction(LVEF) in the two groups were measured. Results:The total effective rate was 97.41% in the treatment group,higher than that of 88.79% in the control group,the difference being significant(P<0.05). After treatment,Chinese medicine syndrome scores in the two groups were decreased when compared with those before treatment(P<0.05), and the score in the treatment group was lower than that in the control group(P<0.05). After treatment,the levels of LVEDD and LVESD in the two groups were decreased when compared with those before treatment(P<0.05),and LVEF levels were increased(P<0.05);the improvement of the above indexes in the treatment group was more significant than that in the control group(P<0.05). Conclusion: Qili Qiangxin capsules combined with routine western medicine for ICM complicated with heart failure has good curative effect and can effectively improve ventricular remodeling of patients and relieve their clinical symptoms.

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陈豫贤,于淑君,代聚平.芪苈强心胶囊联合常规西药治疗缺血性心肌病伴心力衰竭临床研究[J].新中医,2021,53(15):40-43

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  • 在线发布日期: 2021-08-10
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