Abstract：Objective：To observe the clinical effect of Jiao'ai Hutai tang combined with progesterone injection for patients with threatened abortion complicated with subchorionic hematoma， and its effect on the contents of progesterone(P) and human chorionic gonadotropin(HCG) in serum，and maternal-infant outcome. Methods：A total of 90 cases of patients with threatened abortion complicated with subchorionic hematoma were selected as the study objects，and were divided into two groups according to the random number table method，45 cases in each group. The control group was given progesterone， and the observation group was additionally given Jiao'ai Hutai tang based on the treatment of the control group. After treatment，the clinical effect and maternal-infant outcome were observed. Before and after treatment，contents of HCG and P in serum were compared between the two groups. After treatment，the size of subchorionic hematoma，vaginal bleeding duration，and the disappearance time of hematoma were observed in the two groups. Results：The total clinical effective rate was 93.33% in the observation group，higher than that of 77.78% in the control group，the difference being significant(P＜ 0.05). After treatment， contents of HCG and P in serum in the two groups were increased， and the contents in the observation group were higher than those in the control group， the difference being significant(P＜0.05). The size of subchorionic hematoma in the observation group was smaller than that in the control group， vaginal bleeding duration shorter， and the disappearance time of hematoma earlier， differences being significant(P＜0.05). The rate of full- term pregnancy in the observation group was higher than that in the control group， and the incidence of abortion was lower， differences being significant(P＜0.05). Conclusion： In the treatment of threatened abortion complicated with subchorionic hematoma，the therapy of Jiao'ai Hutai tang combined with progesterone injection has a good clinical effect. It can shorten vaginal bleeding duration and regression time of hematoma， reduce size of hematoma， and improve maternal- infant outcome. Its mechanism is probably related to its regulation of contents of HCG and P in serum.