Abstract： Objective： To observe the clinical effect of point massage based on midnight- midday ebb- flow theory combined with pectin for patients with enteral nutrition-related diarrhea. Methods：A total of 80 cases of intensive care unit (ICU) patients who was given enteral nutrition were selected and divided into the treatment group and the control group according to the random number table method，40 cases in each group. The control group was given infusion of Weishuneng pectin through gastric tube before enteral nutrition，and the treatment group was additionally given point massage based on midnight- midday ebb- flow theory additionally. Both groups were treated for 7 days. The clinical effect， the checking diarrhea time，the duration of enteral nutrition，and the hospitalization time in ICU were compared between the two groups. Before and after treatment， the score of enteral nutrition tolerance， 24- hour stool semi- quantitative score(Hart score)， symptom score of diarrhea， and the score of gastrointestinal quality of life index(GIQLI) were compared between the two groups. Results：The total effective rate was 95.00% in the treatment group，higher than that of 80.00% in the control group (P＜0.05). The checking diarrhea time in ICU in the treatment group were shorter than those in the control group(P＜0.05). After treatment，the scores of enteral nutrition tolerance and Hart scores were decreased when compared with those before treatment(P＜0.05). After treatment，the score of enteral nutrition tolerance and Hart score in the treatment group were lower than those in the control group(P＜0.05). After treatment， symptom scores of diarrhea in the two groups were decreased when compared with those before treatment(P＜0.05)， and GIQLI scores were increased(P＜0.05). After treatment， symptom score of diarrhea in the treatment group was lower than that in the control group(P＜0.05)，and GIQLI score was higher(P＜0.05). Conclusion：In the treatment of patients with enteral nutrition-related diarrhea in ICU，the therapy of point massage based on midnight- midday ebb- flow theory combined with pectin can significantly improve their clinical symptoms，shorten the checking diarrhea time，as well as enhance enteral nutrition tolerance and quality of life. · 147 ·